In rodent cortex GABAA receptor (GABAAR)-mediated synapses are a significant source of input onto GABA neurons, and the properties of these inputs vary among GABA neuron subtypes that differ in molecular markers and firing patterns. Some features of cortical interneurons are different between rodents and primates, but it is not known whether inhibition of GABA neurons is prominent in the primat...

CYP3A29 is the most important key enzyme for drug metabolism in pig's liver. Research of the characters of CYP3A29 mRNA expression in Chinese experimental miniature pig's livers is significant for evaluating it whether suitable for experimental model for drug metabolism mediated by human CYP3A4 enzyme. In this study, the levels of CYP3A29 mRNA expression in livers of Bama miniature pigs, Guizho...

The phenomenon of pyroelectric electron emission has been employed to develop miniature x-ray sources, such as the Cool-X by Amptek swww.amptek.com/coolx.htmld. The source strength of a pyroelectric x-ray generator is dependent on the emitted electron energy and current. Similarly, the source strength of a pyroelectric neutron generator will be dependent on the energy and production rate of deu...

BACKGROUND Hemodynamic assistance with a miniature intracardiac pump may fill the treatment gap between use of an intraaortic balloon pump (IABP) and the current, more invasive ventricular assist devices. The objective of this study was to compare the hemodynamic efficacy of a miniature intracardiac pump device with that of IABP. METHODS AND RESULTS Reversible acute mitral regurgitation (AMR)...

Miniature neurotransmission is the transsynaptic process where single synaptic vesicles spontaneously released from presynaptic neurons induce miniature postsynaptic potentials. Since their discovery over 60 years ago, miniature events have been found at every chemical synapse studied. However, the in vivo necessity for these small-amplitude events has remained enigmatic. Here, we show that min...

Kevin Philip Schultze: Advanced System Components for the Development of a Handheld Ion Trap Mass Spectrometer (Under the direction of J. Michael Ramsey) This work describes the development and implementation of system components utilized in a handheld ion trap mass spectrometer (MS). Current state-of-the-art portable mass spectrometers fall in the 30 to 40 lb. range due to their large and heav...