Background: Photodynamic therapy (PDT) is a promising therapeutic modality for the treatment of cancer and other diseases. In this study, the epidermoid carcinoma cell line A431 and the normal fibroblasts were used to investigate whether gold nanoparticles (GNPs) can induce an increase in cell death during PDT using 5-aminolevulinic acid (5-ALA) as a photosensitizer.Methods: Human fibroblast an...

A ntibodies protect against lethal infection by bacteria or nonenveloped viruses such as adenovirus (1). They are secreted by plasma cells at the rate of thousands of molecules per second, and it has long been assumed that they function exclusively in the extracellular milieu. The recent discovery of a cytoplasmic process called antibody-dependent intracellular neutralization (ADIN) put an end ...

A context-aware personalized travel recommendation system based on geotagged social media data mining Abdul Majid a , Ling Chen a , Gencai Chen a , Hamid Turab Mirza a , Ibrar Hussain a & John Woodward b a College of Computer Science, Zhejiang University, 38 Zheda Road, Hangzhou, 310027, PR China b School of Computer Science, The University of Nottingham Ningbo China, Ningbo, 315100, PR China P...

1 Renata Vusilović, DVM, Vukovarska 36, 43280 Garešnica 2 Željka Cvrtila Fleck, DSc, assistant professor; Nevijo Zdolec, DSc, junior researchersenior assistant; Ivana Filipović, DVM, junior research assistant, Lidija Kozačinski, DSc, associate professor; Bela Njari, DSc, full professor, Mirza Hadžiosmanović, DSc, full professor, Department of Hygiene and Technology of Foodstuffs of Animal Origi...

background and aims. orientation of the occlusal plane is one of the most important clinical procedures in prosthodontic rehabilitation of edentulous patients. the aim of this study was to define the best posterior reference point of ala-tragus line for orientation of occlusal plane for complete denture fabrication. materials and methods. fifty-three dental students (27 females and 26 males) wi...

Objective(s): To investigate the association of single nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptors gamma (PPARG) with essential hypertension (EH) and additional role of gene– high-density lipoprotein cholesterol (HDL) interaction. Materials and Methods:A total of 1640 patients with EH (806 males, 834 females), with a mean age of 52.5±12.6 years, were selec...

introduction during the process photodynamic therapy (pdt), bleaching of photosensitizer induced by irradiation and generation of reactive oxygen species (ros) can provide some information concerning the efficiency of treatment. since gold nanoparticles (gnps) have been highlighted as efficient drug delivery systems, in this study, by utilizing gnps conjugated with 5 aminolevulinic acid (5-ala-...