نتایج جستجو برای: mitochondrial deletions

تعداد نتایج: 150658  

Journal: :Nucleic acids research 1989
I J Holt A E Harding J A Morgan-Hughes

Forty per cent of patients with mitochondrial myopathies, a diverse group of multisystem diseases predominantly affecting skeletal muscle and the brain, have large deletions of a proportion of muscle mitochondrial DNA (mt DNA). These appeared to be identical in 13 of 28 cases, contained within the region 8286-13595 bp. Analysis of the deletion junction in two cases showed a 13 nucleotide sequen...

2013
G R Campbell A Reeve I Ziabreva T M Polvikoski R W Taylor R Reynolds D M Turnbull D J Mahad

AIMS Although mitochondrial abnormalities have been reported within paraspinal muscles in patients with axial weakness and neuromuscular disease as well as with ageing, the basis of respiratory deficiency in paraspinal muscles is not known. This study aimed to determine the extent and basis of respiratory deficiency in paraspinal muscles from cases undergoing surgery for degenerative spinal dis...

Journal: :MHR: Basic science of reproductive medicine 2005

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