1. The serum of rabbits treated intravenously with neosalvarsan, and of syphilitic patients treated intravenously with salvarsan or neosalvarsan, has a definite spirochaeticidal action upon Spirochoeta duttoni. 2. Although this spirochaeticidal action is exerted in vitro, it can be demonstrated only after the treated spirochaetae are injected into susceptible animals. 3. A curative action of th...

A new, two-dimensional overtone mobility spectrometry (OMS-OMS) instrument is described for the analysis of complex peptide mixtures. OMS separations are based on the differences in mobilities of ions in the gas phase. The method utilizes multiple drift regions with modulated drift fields such that only ions with appropriate mobilities are transmitted to the detector. Here we describe a hybrid ...

Using longitudinal data from the 4-H Study of Positive Youth Development, the authors assessed 1,977 adolescents across Grades 5 to 8 to determine if there were distinctive developmental paths for behavioral and emotional school engagement; if these paths varied in relation to sex, race/ethnicity, and family socioeconomic status (SES); and whether links existed between trajectories of school en...

Sixty-two beagle dogs were given three doses of acetaminophen over a period of 24 hr in a fulminant liver failure model that is 70% lethal in 72 hr. Treatment of the animals with hepatic stimulatory substance alone or in a mixture with insulin, transforming growth factor-alpha and insulin-like growth factor II had no effect on mortality. Evidence of maximum regeneration with a mitotic index 20 ...

The present review describes ways in which ultrasonic vocalizations (USVs) have been used in studies of substance abuse. Accordingly, studies are reviewed which demonstrate roles for affective processing in response to the presentation of drug-related cues, experimenter- and self-administered drug, drug withdrawal, and during tests of relapse/reinstatement. The review focuses on data collected ...

In industries which employ solvents containing benzene, determination of the atmospheric content of this substance is an important and constant health problem. Many of the methods of assessing benzene concentration described in the literature, including those of Jacobs (1949) and Elkins (1950), entail determination of the total aromatic content, and estimation of the atmospheric benzene concent...

BACKGROUND The compatibility study of active substances with excipients finds an important role in the domain of pharmaceutical research, being known the fact that final formulation is the one administered to the patient. In order to evaluate the compatibility between active substance and excipients, different analytical techniques can be used, based on their accuracy, reproducibility and fastn...

since the waste of agricultural and horticultural products is high, appropriate methods should be used to produce products with high quality and shelf life for export. in iran a great part of fruits and vegetables are dried conventionally and farmer use so2 gas for preservation and color stability of dried apricots ,but this gas is allergic and carcinogenic and effort to find suitable substitut...

abstract   background: patients with addictions have many acute and chronic medical illnesses, both related and unrelated to their addictions. in spite of high incidence of substance-related disabilities, substance abuse is usually underdiagnosed in general hospitals. the objective of the present study was to investigate the frequency and pattern of substance use in patients with different medi...

In an attempt to understand the role of Ca2+ on the bioactive conformation of peptide hormones, we have examined the interaction between Ca2+ and the neuropeptide substance P. Using CD spectroscopy to monitor conformational changes caused by Ca2+ binding, we found no significant binding of the cation by substance P in water. However, a substantial conformational change occurred in the hormone o...