An alginate (named P1) prepared from Sargassum fusiforme has been proven to have significant anti-photoaging activity in our previous study. In this study, lyase was used obtain P1 hydrolysates with different molecular weights, and their structural characteristics were compared. Results showed that lyases could rapidly degrade the weight of slightly changed its chemical composition. Fourier tra...

Highlights . Elevated levels of matrix metalloproteinases 2 and 9 are associated with the initiation severity CHF developed after breast cancer therapy anthracyclines, which may contribute to cardiac remodeling progression systolic dysfunction. Concentrations metalloproteinases-2 -9 in blood serum serve as predictors unfavorable course anthracycline-induced heart failure. Aim To assess role (MM...

The purpose of the current study was to analyze synovial fluid concentrations known inflammatory biomarkers in setting symptomatic osteoarthritis (OA) knee and assess for any differences biomarker based on extent radiographic disease. Patients presenting with complaints were invited provide samples from during their initial office visit. For this study, a subset patients OA analyzed. concentrat...

The corpus luteum (CL) offers the opportunity to study high proliferative processes during its development and degradation processes during its regression. We examined the mRNA expression of matrix metalloproteases (MMP)-1, MMP-2, MMP-9, MMP-14, MMP-19, tissue inhibitor of MMP (TIMP)-1, TIMP-2, tissue plasminogen activator (tPA), urokinase plasminogen activator (uPA), uPA-receptor (uPAR), PA-in...

The aim of this study was to identify the possible correlation between polymorphisms in matrix metalloproteinase (MMP)-1 and MMP-3 and their corresponding protein levels in disc tissues obtained from patients with lumbar disc herniation (LDH) using biochemical and immunohistochemical analyses. Blood and disc samples were obtained from 100 patients with LDH who underwent a lumbar microdiscectomy...

OBJECTIVE Matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMP) have been found in high concentrations in pleural effusions. Because MMP and TIMP may play a part in the causation of the fibrosis seen in tuberculous (TB) pleuritis their occurrence was examined. DESIGN Pleural effusion fluid and plasma concentrations of MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, TIMP-1 and ...

Background: The aim of the study was to longitudinally evaluate association between MMP-2, MMP-9, TIMP-1 and chest radiological findings in COVID-19 patients. Methods: patients were evaluated based on their hospital admission (baseline) three months after discharge (T post) stratified into ARDS non-ARDS groups. As a control group, healthy donors (HD) enrolled. Results: At baseline, compared HD ...