IMPORTANCE Surgical excision of skin cancer is a common treatment, yet the proper surgical margin remains unclear. This study reviews data on lesions and their margins as defined by Mohs micrographic surgery. OBJECTIVE To review margins as defined by Mohs micrographic surgery. DESIGN Retrospective review of data from patients with skin cancer. SETTING Academic medical center. PARTICIPAN...

INTRODUCTION Mohs surgery was first described by Frederic Mohs in 1941 to eliminate high-risk cutaneous tumors. The technique involves histological examination of the margins. OBJECTIVE The aim of this study was to describe the clinical findings and compare the grade and subclinical extension of the tumor as measured by the number of Mohs stages needed for complete elimination according to wh...

BACKGROUND With the advent of incorporating the immunoperoxidase staining technique into the processing of frozen tissue, the use of Mohs micrographic surgery (MMS) has been expanded to include several high-risk tumors such as lentigo maligna, malignant melanoma, and dermatofibrosarcoma protuberans. OBJECTIVES To thoroughly review the English medical literature pertaining to the use of immuno...

Mohs chemosurgery, using the fixed-tissue technique, was proposed for the treatment of melanoma by Frederic Mohs in 1950.[1] In numerous publications since, Mohs reported cure rates at least comparable to those obtained with the conventional surgical therapies of the time. Initially, Mohs believed that the in situ tissue fixation with zinc chloride paste inherent in the fixed-tissue technique w...