Chemiluminescence (CL) is a very promising method for applications in analytic chemistry and biological systems due to the elimination of external light source, which could reduce autofluorescence interference improve signal-to-noise ratio (SNR) tissue penetration depth. The fluorescent dyes, chemiluminescent initiator, reaction temperature are three crucial factors that determine chemiluminesc...

The natural stiffness of DNA, which contributes to the interactions of the many proteins involved in its biological processing and packaging, also plays an important role in modern nanotechnology. Here we report new Monte-Carlo simulations of deformable DNA molecules of potential utility in understanding the behavior of the long, double-helical polymer in the tight confines of a cell and in the...

[reaction: see text] A new near-infrared (NIR) fluorescent molecular probe derived from indocarbocyanine dye and galactose was prepared, and the procedure was optimized. The presence of a nonionic polyhydroxyl moiety between hydrophobic groups enhances solubility and possibly minimizes aggregation in aqueous solutions. The structural framework of this molecule provides multivalent sites for lab...