A study consisting of two trials was conducted to determine the effects of monensin on the apparent absorption and retention of magnesium (Mg), phosphorus (P), calcium (Ca) and zinc (Zn) and to determine mineral changes in tissue and ruminal fluid. Eight lambs (39 kg) were used in trial 1, and 10 lambs (37 kg) were used in trial 2. Animals were blocked by weight and fed a high concentrate diet ...

Essential oils (EOs) from plant extracts have been reported to have an antibacterial activity against gram-negative and gram-positive bacteria. Several of the gram-positive bacteria are involved in ruminal biohydrogenation of fatty acids (FAs), thus suggesting that feeding EOs could lower biohydrogenation of FA because of a decrease in the number of bacteria involved in that process. As a resul...

It is demonstrated that crotonyl-CoA reductase (CCR) plays a significant role in providing methylmalonyl-CoA for monensin biosynthesis in oil-based 10-day fermentations of Streptomyces cinnamonensis. Under these conditions S. cinnamonensis L1, a derivative of a high-titre producing industrial strain C730.1 in which ccr has been insertionally inactivated, produces only 15 % of the monensin yield...

In this paper structural and microbiological studies on the ionophorous antibiotic monensin A and its derivatives have been collected. Monensin A is an ionophore which selectively complexes and transports sodium cation across lipid membranes, and therefore it shows a variety of biological properties. This antibiotic is commonly used as coccidiostat and nonhormonal growth promoter. The paper foc...

the objective of this study was to determine the effects of feeding different levels of monensin on feed intake, milk production and composition, and milk fattyacid profile in lactating holstein cows. four multiparous cows averaging 517 ± 47 (sd) kg in body weight and 101 ± 19.8 (sd) days in milk were housed individually in tie-stalls. the study was conducted as a 4 × 4 latin square design for ...

Degree of unsaturation of fatty acids, which is influenced by lipid source and level of metabolism in the rumen, is a major determinant in how dietary lipids affect genes that regulate beef marbling. A total of 28 Red Norte bulls with an initial live weight of 361±32 kg (P>0.05) were used in a completely randomized experimental design to analyze the expression of genes that are involved in lipi...

The effect of Monensin (Rumensin, Eli Lilly & Co.) in incubations with mixed rumen microorganisms metabolizing carbohydrate or protein substrates was investigated. Monensin partly inhibited methanogenesis and increased propionate production, although the effect was not always statistically significant. Incubations with substrates specific for methane bacteria suggest that inhibition of methanog...

in this research, effects of adding methafix (containing malate and fumarate as organic acids) with or without monensin in diet of fattening farahani lamb's on performance, and plasma concentration of some metabolites and minerals were investigated. twenty-four male lambs (4-6 months old, 35.9 ±7.4 kg) were randomly  assigned to; 1) control diet (control), 2) control with 24 mg of monensin...

The objective of this study was to determine the long-term effects of feeding monensin on methane (CH4) production in lactating dairy cows. Twenty-four lactating Holstein dairy cows (1.46 +/- 0.17 parity; 620 +/- 5.9 kg of live weight; 92.5 +/- 2.62 d in milk) housed in a tie-stall facility were used in the study. The study was conducted as paired comparisons in a completely randomized design w...

Three experiments were conducted to evaluate the effects of diet and monensin on performance, digestibility, and methane production in steers fed forage-based diets. In Exp. 1, 72 individually fed steers (300 ± 25 kg) were used in a randomized block design arranged as 2 separate 2 × 2 factorials with two common treatments, thus 6 diets were fed with 12 steers per treatment. Factors included hig...