نتایج جستجو برای: msp

تعداد نتایج: 2571  

2013
F Sperotto S Brachi G Cuffaro M Seguso F Vittadello F Zulian

Introduction Chronic Musculoskeletal Pain (MSP) in children can be due to various non-inflammatory conditions, such as the benign joint hypermobility syndrome (BJHS) or idiopathic MSP (IMSP). MSP heavily influences patient’s quality of life and is often misdiagnosed or included in the vast category of unspecific MSP. A careful differential diagnosis and knowledge of possible risk factors are ne...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1997
I A Scarisbrick M D Towner P J Isackson

A full-length cDNA clone of a previously unidentified serine protease, myelencephalon-specific protease (MSP), has been isolated by using a PCR cloning strategy and has been shown to be expressed in a nervous system and spinal cord-specific pattern. Sequence analysis demonstrated that MSP is most similar in sequence to neuropsin, trypsin, and tissue kallikrein and is predicted to have trypsin-l...

Journal: :The Journal of infectious diseases 2008
Carlota Dobaño Stephen J Rogerson Margaret J Mackinnon David R Cavanagh Terrie E Taylor Malcolm E Molyneux Jana S McBride

Cerebral malaria (CM) and severe malarial anemia (SMA) are 2 major causes of death in African children infected with Plasmodium falciparum. We investigated levels of naturally acquired antibody to conserved and variable regions of merozoite surface protein (MSP)-1 and MSP-2, apical membrane antigen (AMA)-1, and rhoptry-associated protein 1 in plasma samples from 126 children admitted to the hos...

Journal: :Infection and immunity 2002
Alan L Y Pang Caryn N Hashimoto Leslie Q Tam Z Q Meng George S N Hui Walter K K Ho

The 42-kDa carboxyl-terminal processing fragment of Plasmodium falciparum merozoite surface protein 1 (MSP-1(42)) is an anti-erythrocytic stage malaria vaccine candidate. In this study, MSP-1(42) was expressed by using the Bombyx mori nuclear polyhedrosis virus-silkworm expression system, and the antigenicity and immmunogenicity of the recombinant protein, Bmp42, were evaluated. The average yie...

2014
Kanungnit Congpuong Thirasak Hoonchaiyapoom Kornnarin Inorn

Genetic characteristics of Plasmodium falciparum may play a role in the treatment outcome of malaria infection. We have studied the association between diversity at the merozoite surface protein-1 (msp-1), msp-2, and glutamate-rich protein (glurp) loci and the treatment outcome of uncomplicated falciparum malaria patients along the Thai-Myanmar border who were treated with artemisinin derivativ...

2013
Michelle B. Visser Chun-Xiang Sun Adeline Koh Richard P. Ellen Michael Glogauer

The major outer sheath protein (Msp) of Treponema denticola inhibits neutrophil polarization and directed chemotaxis together with actin dynamics in vitro in response to the chemoattractant N-formyl-methionine-leucine-phenylanine (fMLP). Msp disorients chemotaxis through inhibition of a Rac1-dependent signaling pathway, but the upstream mechanisms are unknown. We challenged murine bone marrow n...

Journal: :Development 2003
Alison Forgie Sean Wyatt Pamela H Correll Alun M Davies

Macrophage stimulating protein (MSP) is a pleiotropic growth factor that signals via the Ron receptor tyrosine kinase. We report that Ron mRNA is expressed by NGF-dependent sensory and sympathetic neurons and that these neurons survive and grow with MSP at different stages of development. Whereas NGF-dependent sensory neurons become increasingly responsive to MSP with age, sympathetic neurons e...

Journal: :iranian journal of parasitology 0
a. miahipour department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran. h. keshavarz department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran and center for research of endemic parasites of iran (crepi), tehran university of medical sciences, tehran, iran. a. heidari department of pathobiology, school of medicine, alborz university of medical sciences, karaj, iran. a. raeisi department of medical entomology and vector control, school of public health, tehran university of medical sciences, tehran, iran. m. rezaeian department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran and center for research of endemic parasites of iran (crepi), tehran university of medical sciences, tehran, iran. s. rezaie department of medical parasitology and mycology, school of public health, tehran university of medical sciences, tehran, iran and department of medical biotechnology, school of advanced technologies in medicine, tehran university of medical sciences, tehran, iran.

b ackground: the main goal of present study was to detect polymorphism in msp-1 gene which is a major blood stage candidate for vaccine in plasmodium vivax by single strand conformational poly- morphism-polymerase chain reaction (sscp-pcr). m ethods: during 2008 to 2010 fifty samples were collected from iranian patients with p. vivax in hormozgan province, southern iran. all of the samples were...

2011
Michelle B. Visser Adeline Koh Michael Glogauer Richard P. Ellen

The major outer sheath protein (Msp) of Treponema denticola perturbs actin dynamics in fibroblasts by inducing actin reorganization, including subcortical actin filament assembly, leading to defective calcium flux, diminished integrin engagement of collagen, and retarded cell migration. Yet, its mechanisms of action are unknown. We challenged Rat-2 fibroblasts with enriched native Msp. Msp acti...

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