Recent studies have investigated the use of anti-inflammatory cytokine, interleukin 10 (IL-10) to control the development of disseminated intravascular coagulation (DIC) in sepsis by down-regulation of monocyte tissue factor (MTF) induced by lipopolysaccharide (LPS) in the initial phase of the disease. In vitro and in vivo human studies have shown that a minimal (<1 h) delay in IL-10 treatment ...

The zinc finger transcription factor MTF-1 is essential for proper response to heavy metal load and other stress conditions in vertebrates, and also contributes to the maintenance of the cellular redox state. Target genes include metallothioneins (MT-I and MT-II) and gamma-glutamylcysteine synthetase (gamma-GCS), an enzyme involved in glutathione biosynthesis. Although MTF-1 is expressed ubiqui...

A simple variant of the edge method to determine the presampled modulation transfer function (MTF) of digital imaging detectors has been developed that produces sufficiently accurate MTF values for frequencies up to the Nyquist frequency limit of the detector with only a small amount of effort for alignment and computing. An oversampled edge spread function (ESF) is generated from the image of ...

The specific formylation of initiator methionyl-tRNA by methionyl-tRNA formyltransferase (MTF; EC 2.1.2.9) is important for the initiation of protein synthesis in eubacteria and in eukaryotic organelles. The determinants for formylation in the tRNA are clustered mostly in the acceptor stem. As part of studies on the molecular mechanism of recognition of the initiator tRNA by MTF, we report here...

The modulation transfer function (MTF) is widely used as the image quality criterion of choice for imaging applications where fine detail in extended images needs to be specified or evaluated. We present a parametric analysis of the effect of scattered light upon the MTF of an imaging system and illustrate the results for three specific applications: (1) a visible Newtonian telescope with moder...

A neutral mononuclear Fe(II) complex with spin crossover (SCO) properties, Fe2(SCN)2 (1) (L = 2-(2-(trifluoromethyl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline), was solvothermally synthesized. It displays a new example of two-step SCO with Tc1↓ = 250 K, Tc1↑ = 260 K and Tc2 = 295 K.

O avanço da radiologia digital proporcionou uma melhoria significativa à qualidade das imagens radiológicas. Essa evolução trouxe muitos benefícios para o diagnóstico por imagem como a agilidade do processo, resolução espacial, diminuição tempo necessário de exposição, entre outros. Os últimos trabalhos publicados mostraram que função transferência modulação ou MTF (Modulation Transfer Function...

The edge method for measuring the modulation transfer function (MTF) has recently gained popularity due to its simplicity and appropriateness particularly for digital imaging systems. Often edge test devices made of rather thin metal sheets are used, which are semitransparent to x rays and may generate scattered radiation. The effect of this scattered radiation on the determined MTF was investi...

We measured the modulation transfer function (MTF) of a lens in the visible region using a random test target generated on a computer screen. This is a simple method to determine the entire MTF curve in one measurement. The lens was obscured by several masks so that the measurements could be compared with the theoretically calculated MTF. Excellent agreement was obtained. Measurement noise was ...

A method for conditioning data used in the measurement of the modulation transfer function (MTF) is discussed. This method is based upon imposing the constraint that the edge spread function (ESF) is monotonic. The advantages of this technique, when applicable, are demonstrated with simulated examples for which the true MTF is known. The application of this technique in the measurement of the M...