mthfd1

Polymorphisms in folate pathway genes may influence the susceptibility to acute lymphoblastic leukemia (ALL). DNA was isolated from 245 pediatric ALL patients (cases) and from 500 blood bank donors (controls). Polymorphisms in methylene-tetrahydrofolate reductase (MTHFR 677C>T, 1298A>C), methionine synthase (MTR 2756A>G), methionine synthase reductase (MTRR 66A>G), methylenetetrahydrofolate deh...

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Is MTHFD1 polymorphisms rs 2236225 (c.1958G>A) associated with the susceptibility of NSCL/P? A systematic review and meta-analysis

Journal: :F1000Research 2015

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Is MTHFD1 polymorphism rs 2236225 (c.1958G>A) associated with the susceptibility of NSCL/P? A systematic review and meta-analysis

Journal: :F1000Research 2016

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Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis.

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009

Simon M Collin Chris Metcalfe Luisa Zuccolo Sarah J Lewis Lina Chen Angela Cox Michael Davis J Athene Lane Jenny Donovan George Davey Smith David E Neal Freddie C Hamdy Julius Gudmundsson Patrick Sulem Thorunn Rafnar Kristrun R Benediktsdottir Rosalind A Eeles Michelle Guy Zsofia Kote-Jarai Jonathan Morrison Ali Amin Al Olama Kari Stefansson Douglas F Easton Richard M Martin

Folate-pathway gene polymorphisms have been implicated in several cancers and investigated inconclusively in relation to prostate cancer. We conducted a systematic review, which identified nine case-control studies (eight included, one excluded). We also included data from four genome-wide association studies and from a case-control study nested within the UK population-based Prostate Testing f...

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