We describe a general multinuclear (1H, 23Na, 87Rb) NMR approach for direct detection of alkali metal ions bound to G-quadruplex DNA. This study is motivated by our recent discovery that alkali metal ions (Na+, K+, Rb+) tightly bound to G-quadruplex DNA are actually "NMR visible" in solution (Wong, A.; Ida, R.; Wu, G. Biochem. Biophys. Res. Commun. 2005, 337, 363). Here solution and solid-state...

This review summarizes the data on stereochemical structure of functionalized azoles (pyrazoles, imidazoles, triazoles, thiazoles, and benzazoles) related compounds obtained by multipulse multinuclear 1H, 13C, 15N NMR spectroscopy quantum chemistry. The stereochemistry is a challenging topic theoretical research, as correct interpretation their chemical behavior biological activity depends unde...

Herein we report on a series of bulky bis(alkyl)- and bis(silyl)- substituted polysilanes. Moreover, performed desilylation dechlorination experiments with them. These compounds were characterized by multinuclear NMR spectroscopy, mass spectrometry, X-ray crystallography. It was found that the selective formation silyl mono- di-anions is crucial for successful isolation these utilized multiple ...

Although some of the platinum(II/IV) and rhodium(III) chemistry is considered ‘old’ and wellknown, the application of modern multinuclear NMR spectroscopic methods to this chemistry in solution reveals new details about their rich and relevant solution chemistry. In this paper we will briefly illustrate that the highly-sensitive 195 Pt NMR shielding is an excellent probe to explore aspects such...

This work determines the potential of solid-state NMR techniques to probe proton, alkali, and niobium environments in Lindqvist salts. Na7HNb6O19·15H2O (1), K8Nb6O19·16H2O (2), and Na8Ta6O19·24.5H2O (3) have been studied by solid-state static and magic angle spinning (MAS) NMR at high and ultrahigh magnetic field (16.4 and 19.9 T). (1)H MAS NMR was found to be a convenient and straightforward t...

Alkaline solutions containing polyhydroxy carboxylates and Ca(II) are typical in cementitious radioactive waste repositories. Gluconate (Gluc(-)) is a structural and functional representative of these sugar carboxylates. In the current study, the structure and equilibria of complexes forming in such strongly alkaline solutions containing Ca(2+) and gluconate have been studied. It was found that...

Preparation and characterization of two new triptycene based polytopic Pt(II) organometallic complexes are being reported. These complexes have three trans-bromobis(trialkylphosphine)platinum(II) units directly attached to the central triptycene unit. These organoplatinum complexes were converted to the corresponding nitrate salts for subsequent use in self-assembly reactions. Characterization ...

New divalent lanthanoid and alkaline earth metal complexes bearing the 1,3-bis(diphenylphosphano)cyclopentadienyl ligand have been synthesised using redox-transmetallation protolysis (RTP) approach. From reaction of corresponding metal, diphenylmercury proligand C5H4(PPh2)2, compounds [M(η5-C5H3(PPh2)2-1,3)2(S)] (with M = Yb, S (thf)2 or Eu, Ca, Sr, Ba, dme) were isolated characterised by X-ray...

A set of C,N-intramolecularly coordinated boranes containing various C,N-chelating ligands L(1-3) (where L(1) = [o-(CH=NtBu)C6H4], L(2) = [o-(CH=N-2,6-iPr2C6H3)C6H4], L(3) = [o-(CH2NMe2)C6H4]); L(1-3)BCl2 (for 1 L = L(1), for 2 L = L(2), for 5 L = L(3)), L(1)BPhCl (3) and L(1)BCy2 (4) (where Cy = cyclohexyl) were synthesized and fully characterized by multinuclear NMR spectroscopy and in cases ...