Fractures are among the most common human traumas. Fracture healing represents a unique temporarily definable post-natal process in which to study the complex interactions of multiple molecular events that regulate endochondral skeletal tissue formation. Because of the regenerative nature of fracture healing, it is hypothesized that large numbers of post-natal stem cells are recruited and contr...

Sports-related maxillofacial fractures were analysed in 80 patients, accounting for 5.6% of all patients with facial bone fractures, treated during the 5-year period 1981-1985. 55% of the patients had 1 or more mandibular fractures and 45% had midface fractures. 6% of the patients had multiple injuries. The most common causes of injury were collision and fall. Soccer and ice hockey turned out t...

This patient is a 56-year-old woman with a history of IGG κ multiple myeloma diagnosed 15 years prior to admission. She had widespread lytic bone lesions and pathological fractures, which remarkably had not been accompanied by significant pain, but were mostly refactory to chemotherapy.

To determine how fracture–vuggy structure, pressure, and injection–production mode influence displacement efficiency in the water flooding process in fracture–vuggy reservoirs, two types of models were built based on the characteristic of such reservoir: two fracture models with different fracture apertures and two fracture– vuggy models with different sizes of vugs. A series of twophase fluid ...

The usual terrible triad of the elbow consists of posterior dislocation of the elbow, radial head fracture and coronoid fracture. We describe a new variant of the terrible triad of the elbow consisting of fracture of the capitellum involving the full length of the trochlea and posterolateral dislocation of the elbow associated with coronoid fracture (type 1 Regan-Morrey). A 25-year-old girl was...

CONTEXT The RANK/RANKL/OPG signalling pathway is important in the regulation of bone turnover, with single nucleotide polymorphisms (SNPs) in genes within this pathway associated with bone phenotypic adaptations. OBJECTIVE To determine whether four SNPs associated with genes in the RANK/RANKL/OPG signalling pathway were associated with stress fracture injury in elite athletes. DESIGN, PARTI...

background:   although intramedullary nailing (imn) is an established and accepted operative treatment for femoral shaft fracture in patients younger than 60, there is a lack of data on the results of this treatment on those over 60. the purpose of this study was to determine if the outcome of imn for femoral shaft fracture in elderly patients is also acceptable. particular challenges in this g...

where δif only needs to be accounted for if the applied loads influence the virtual crack rotation, e.g. due to crack face tractions and body-type loads. Also, it is worth observing that, non-zero contributions to the variations δiK, δif occur only in those elements that experience the virtual crack rotation. The rates of the energy release rate, Hsij are obtained by differentiating Gsi in (5) ...

We present a multiple-scale approach for the analysis of tensile failure of concrete under impact loading. A phenomenological rate dependent constitutive model is applied at the macroscopic level. Viscosity terms are included to represent the strengthening effect associated with the microstructural moisture and inertial effects of micro-cracking. A partial length scale effect is extracted from ...

Bone injury induces an inflammatory response that involves neutrophils, macrophages and other inflammatory cells. The recruitment of inflammatory cells to sites of injury occurs in response to specific signaling pathways. The CC chemokine receptor type 2 (CCR2) is crucial for recruiting macrophages, as well as regulating osteoclast function. In this study, we examined fracture healing in Ccr2-/...