نتایج جستجو برای: multipotent
تعداد نتایج: 4785 فیلتر نتایج به سال:
In mucopolysaccharidosis-I (MPS-I), alpha-L-iduronidase deficiency leads to progressive heparan sulfate (HS) and dermatan sulfate (DS) glycosaminoglycan (GAG) accumulation. The functional consequences of these accumulated molecules are unknown. HS critically influences tissue morphogenesis by binding to and modulating the activity of several cytokines (eg, fibroblast growth factors [FGFs]) invo...
A new hypothesis for the origin of metastases is presented. It assumes that a cancer-transformed gene in a primary tumour is incorporated in its identical form via a virus-vector function into biologically potent recipient cells in other organs, such as stem cells, multipotent cells or cells in an early phase of division. The origin of metastases may thus possibly occur via a genetic pathway.
Abstract Tissue-resident memory CD8 +T cells (Trm) reside in non-lymphoid tissues and provide potent protection from re-infection. They are multipotent have diverse functions, including effector roles during Using a series of RNA-seq, ATAC-seq, ChIP-seq CUT&RUN experiments, we investigated Bcl11b-dependent molecular mechanisms governing the differentiation small intestine Trm cells. Mice wi...
The germline of multicellular animals is segregated from somatic tissues, which is an essential developmental process for the next generation. Although certain ecdysozoans and chordates segregate their germline during embryogenesis, animals from other taxa segregate their germline after embryogenesis from multipotent progenitor cells. An overlapping set of genes, including vasa, nanos and piwi,...
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