Rupture of advanced human atherosclerotic plaques can precipitate coronary thrombosis, myocardial infarction, and sudden death, but insights into the causes and treatment of plaque rupture have been hampered by lack of a suitable animal model. Particularly desirable would be a model of plaque rupture that would take advantage of current and forthcoming mouse mutant alleles. It is therefore of c...

A recent study describing unique effects of myostatin inhibition on a severely dystrophic (mdx) muscle, and independent experiments showing that branched fibers are uniquely sensitive to activity-induced membrane rupture, have led new hypothesis pathogenesis. This states the absence dystrophin directly results in some degree unrestrained satellite cell activation is not dependent upon prior fib...

Spontaneous chordae rupture of the tricuspid valve is relatively rare, unlike the mitral valve. We present a 27-year-old male with chronic renal failure on hemodialysis therapy for treatment of parathyroid adenoma. The echocardiography showed the severe tricuspid regurgitation with chordae rupture which was not noted 1 year ago. In addition, the papillary muscle of both mitral and tricuspid val...

Introduction: In 1883 Powell in The Lancet for the first time described a clinical condition incurred during lawn tennis, and which involved a calf injury that most commonly resulted from sprinting acceleration or a sudden change in running direction, and which hence became known under the name “tennis leg”. In the present case report we describe for the first time how, a similar injury arises ...

BACKGROUND Tendon-repair techniques have evolved to increase the construct strength of the repair site in order to permit early active range of motion without tendon gap or rupture. The present study evaluated the hypothesis that the injection of botulinum neurotoxin type-A (BoNT-A) into the gastrocnemius muscle will reduce the active force production of that muscle below the force required to ...

1. Prieto JA, Olalla JJ, Enríquez Giraudo P, Ruiz Delgado B. Insuficiencia mitral por rotura aislada de músculo papilar secundaria a traumatismo torácico cerrado. Rev Esp Cardiol. 1995;48:486-8. 2. Parmley LF, Manion WC, Mattingly TW. Nonpenetrating traumatic injury of de heart. Circulation 1958;18:371-96. 3. Simmers TA, Meijburg HW, de la Riviere AB. Traumatic papillary muscle rupture. Ann Tho...

A 19-year-old female collegiate rower presented with a new, painful mass along her right anterolateral chest wall after competition. The patient was diagnosed with a rupture of the serratus anterior muscle from its costal attachments, as confirmed by magnetic resonance imaging. The patient fully recovered after a period of rest followed by a graduated 2-month physical therapy regimen consisting...

This case demonstrates a rare variation in the pattern of injury and the presentation of acute lateral compartment syndrome of the leg. Although uncommon, lateral compartment syndrome of the leg after an ankle inversion leading to peroneus longus muscle rupture has been previously documented. This case was unusual because there was no overt ankle injury and the patient was able to continue phys...

RUPTURE of a papillary muscle is a rare complication of myocardial infarction.1 2 The combination of coronary artery disease with severe mitral regurgitation usually results in a rapid, deteriorating course. Not until 1948 was this diagnosis correctly made ante mortem.3 Sanders et al., in 1957, discussed 61 cases of rupture of a papillary muscle and pointed out the important clinical features o...

ince the introduction of transvenous cardiac pacing S by Furman and Schwedell in 1959, numerous reports of unusual complications have appeared. To o w knowledge, rupture of a papillary muscle o r any valvular component has not been reported previously. This report describes a case of mitral valve papillary muscle rupture upon removal of a transvenous pacing electrode. Furthermore, this patient ...