نتایج جستجو برای: myocardial biomarkers

تعداد نتایج: 255279  

2016
Xuefei Duan Yucheng Chen Tianjing Zhang

Background Diffuse myocardial fibrosis is an important pathophysiological process involved into essential hypertension which may increase myocardium stiffness, cause ventricular remodeling and increase adverse cardiovascular risk eventually. It is strongly evident that optimal antihypertensive therapy will reduce the risk induced by hypertension, however, very few proportion of patients with hy...

2014
Graham J Fent Hazlyna Kamaruddin Pankaj Garg Ahmed Iqbal Nicholas F Kelland Ian R Hall

A diagnosis of myocardial infarction is made using a combination of clinical presentation, electrocardiogram and cardiac biomarkers. However, myocardial infarction can be caused by factors other than coronary artery plaque rupture and thrombosis. We describe an interesting case presenting with hypertensive emergency and type 2 myocardial infarction resulting from Pheochromocytoma associated wit...

2016
Benedict T Costello Leah M Iles Dion Stub Andris Ellims Karen Smith Stephen Bernard Ziad Nehme Janet Bray Peter Cameron Ian Meredith David Kaye Andrew Taylor

Background Late gadolinium enhancement (LGE) with CMR is commonly assumed to represent myocardial fibrosis; however, comparative human histological data are limited, and there is no consensus on the most accurate method for LGE quantitation. We evaluated the relationship between CMR assessment of regional fibrosis and infarct size assessment using serial biomarkers after ST segment elevation my...

2014
Chao Cheng Qiang Wang Wenjie You Manhua Chen Jiahong Xia

BACKGROUND Recent studies have demonstrated that acute myocardial infarction induces a distinctive miRNA signature, suggesting that miRNAs may serve as diagnostic markers. Although many studies have investigated the use of miRNAs in the detection of cardiac injury, some had small sample sizes (<100 patients) or reported different results for the same miRNA. Here, the role of circulating miRNAs ...

Journal: :World journal of pediatrics : WJP 2015
Masaya Sugimoto Seiko Kuwata Clara Kurishima Jeong Hye Kim Yoich Iwamoto Hideaki Senzaki

BACKGROUND Most congenital heart diseases (CHDs) have specific hemodynamics, including volume and pressure overload, as well as cyanosis and pulmonary hypertension, associated with anatomical abnormalities. Such hemodynamic abnormalities can cause activation of neurohormones, inflammatory cytokines, fibroblasts, and vascular endothelial cells, which in turn contribute to the development of path...

Journal: :Journal of the American College of Cardiology 2011

Journal: :European Heart Journal 2022

Abstract Introduction Acute myocardial infarction (AMI) is still one of leading cause for mortality and disability in cardiovascular disease [1]. Autophagy an intracellular mechanism involved the elimination recycling proteins organelles by lysosomes [2]. has important role critical cellular process self-protective degradation components ischemic events such as AMI left ventricular remodeling [...

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