introduction: although left ventricular(lv) function parameters measured by gated myocardial perfusion spect (gspect) have been validated, experimental data have revealed that the calculated the lv function parameters using gspect are affected by patient populations as well as particular acquisition and processing conditions. we tried to determine the normal values of gspect in an iranian popul...

OBJECTIVE To assess the prevalence of myocardial viability by technetium-99m (Tc-99m)-tetrofosmin/fluorine-18-fluorodeoxyglucose (FDG) single photon emission computed tomography (SPECT) in patients with ischaemic cardiomyopathy. DESIGN A retrospective observational study. SETTING Thoraxcenter Rotterdam (a tertiary referral centre). PATIENTS 104 patients with chronic coronary artery diseas...

UNLABELLED The aim of this study was to compare (99m)Tc-tetrofosmin SPECT with contrast-enhanced MRI (ceMRI), a new direct sign of myocardial fibrosis. METHODS We studied 21 patients (age, 60 +/- 11 y; 19 male) with previous myocardial infarction and severe left ventricular dysfunction (ceMRI EF, 29% +/- 6%). All patients underwent resting and postnitrate (intravenous isosorbide dinitrate) (9...

Over the course of the last two decades, myocardial perfusion with Single Photon Emission Computed Tomography (SPECT) has emerged as an established and well-validated method for assessing myocardial ischemia, viability, and function. Gated-SPECT imaging integrates traditional perfusion information along with global left ventricular function. Despite of these advantages, inherent limitations of ...

BACKGROUND Gated Single Photon Emission Computerized Tomography (SPECT) is a modality which is helpful in the detection of wall motion, thickening and ejection fraction of left ventricle. The purpose of this study was to correlate the ungated and gated SPECT in evaluation of left ventricle dysfunction. METHOD It was a prospective study done at Institute of Radiotherapy and Nuclear Medicine (I...

UNLABELLED Because of the difficulty of predicting the response of patients with idiopathic dilated cardiomyopathy (IDC) to beta-blocker therapy, this study was performed to evaluate whether gated myocardial SPECT (gated SPECT) could be useful for predicting that response. METHODS We performed gated SPECT with (99m)Tc-sestamibi on 38 patients with IDC before treatment with a beta-blocker and ...

The purpose of this study was to validate a semiautomatic method for quantitating the size of relative myocardial perfusion defects from single-photon emission computed tomographic (SPECT) images. We compared the size of the image defect in vivo, expressed as percent of involved left ventricle, as determined by this method with the anatomic size of the defect in vitro in 19 dogs. To test the me...

BACKGROUND We define the repeatability coefficients (RC) of key quantitative and visual perfusion and function parameters that can be derived by the QGS/QPS automated software and by expert visual observer from gated myocardial perfusion SPECT (MPS) scans. METHODS Standard QGS/QPS algorithms have been applied to derive quantitative perfusion and function parameters in 200 99mTc-tetrofosmin re...

UNLABELLED The present study assessed left ventricular performance during dobutamine stress measured using gated SPECT, and compared the results to myocardial perfusion and fatty acid metabolism. METHODS Thirty-six patients with myocardial infarction given (99m)Tc-sestamibi or (99m)Tc-tetrofosmin were examined by gated SPECT at rest and during dobutamine stress (4-20 microg x kg(-1) x min(-1)...