Bone diseases are common among middle-aged and elderly people, harm to activities of daily living (ADL) quality life (QOL) for patients. It is crucial search key regulatory factors associated with the development bone explore potential therapeutic targets diseases. Irisin a novel myokine that has been discovered in recent years. Accumulating evidence indicates irisin beneficial effects treatmen...

Non-alcoholic fatty liver disease (NAFLD) is one of chronic and defines by fat accumulation ≥5% in which can progresses to non-alcoholic steatohepatitis (NASH). NAFLD related obesity as well non obese individuals. Adiponectin a cytokine secreted from adipose tissue involved pathogenesis liked with obesity. Irisin myokine, has convenient effect against metabolic diseases such obesity, disylipemi...