From 2004 to 2014, the Line W moorings measured a 0.7 Sv yr−1 slowing of deep western boundary current (DWBC) offshore Cape Cod. Here, we combine these mooring observations with float and satellite altimeter data find that this DWBC change corresponded cross-basin Atlantic Meridional Overturning Circulation (AMOC) about 0.3 yr−1. Our AMOC transport time series corresponds well Estimating Climat...

The contributions of the hippocampus (HC) and perirhinal cortex (PER) to recognition memory are currently topics of debate in neuroscience. Here we used a rapidly-learned (seconds) spontaneous novel odor recognition paradigm to assess the effects of pre-training N-methyl-D-aspartate lesions to the HC or PER on odor recognition memory. We tested memory for both social and non-social odor stimuli...

Postrhinal (POR) or perirhinal (PER) cortex damage impairs acquisition and expression of contextual fear, but the nature of the impairment remains unclear. This study used a contextual fear discrimination paradigm that biased subjects toward using a configural, rather than an elemental, strategy to distinguish between 2 contexts, I of which was paired with a mild footshock. Control rats discrim...

The Pharmacovigilance Centre Lareb received 621 reports of possible adverse drugs reactions on Diane-35® . Of all reports, 388 were received after media attention. Of the 309 reports of thromboembolic adverse drugs reactions, 18 cases were fatal. In 31 cases the thromboembolic adverse drugs reaction was initially not recognized as such. The analysis and the turmoil of the 'Diane affair' gave ri...

Three experiments examined the effects of perirhinal cortex lesions on rats' retrograde and anterograde memory for object-discriminations and water-maze place-memory problems. In Experiment 1, rats learned two object-discriminations - the first was learned 2 weeks before surgery and the second 24 h before surgery. Rats with perirhinal cortex lesions displayed mildly impaired retention of both o...