Introduction: Rhinoscleroma is caused by Klebsiella pneumoniae subsp. rhinoscleromatis and the ozena infections caused by K. pneumoniae subsp. ozaenae, both infections affect the upper respiratory tract. In the first clinical phases the symptoms are unspecific, and the disease can be misdiagnosed as a common cold, therefore antimicrobial therapy cannot reach effective results and patients must ...

Normal and transformed mouse fibroblasts catalyze transfer of sialic acid, galactose, IV-acetylgalactosamine, N-acetylglucosamine, glucose, and mannose from nucleotide sugar donors to glycolipids and glycoproteins. The enzyme activity is associated with intact cells. Kinetic parameters and optimal ion concentrations have been determined for the glycosyltransferase activities detected when whole...

SV40 large T antigen has been reported to be modified with several different sugars including N-acetylglucosamine, galactose, and mannose. In this report we have reexamined the glycosylation of T antigen and found that while we could detect modification with N-acetylglucosamine, we could not detect any other sugars on the protein. Surprisingly, even though [3H]galactose could be metabolically i...