objective(s): response surface methodology (rsm) by central composite design (ccd) was applied to statistically optimize the preparation of rutin-quercetin (ru-qr) dual drug loaded human hair keratin nanoparticles as well as evaluate the characteristics. materials and methods: the effects of three independent parameters, namely, temperature (x1:10-40 c), surfactant (x2: sds (1), sls (2), tween-...

Response surface methodology (RSM) using a central composite design (CCD) was employed to optimize the conditions for extraction of antioxidants from black soybean (Glycine max var) sprouts. Three influencing factors: liquid-solid ratio, period of ultrasonic assisted extraction and extraction temperature were investigated in the ultrasonic aqueous extraction. Then Response Surface Methodology (...

Ultrasonic technology and response surface methodology (RSM) wereused for optimization of extraction of condensed tannins from the leaf, acron, gland and gall of oak. Three independent variables such as solvent percentage (%), temperature (°C) and time (min) were studied. Effect of methanol concentration was found to be significant on all responses. Optimal ultrasonicassisted extraction (UAE) c...

BTX compounds (Benzene, toluene and xylenes) are the main pollutants in air and fuels. Recent environmental legislations are limited the amount of these materials specially the amount of benzene in gasoline due to its carcinogen effects on health. In this research, the BTX hydrogenation was carried out using nanoparticles of Co supported on MWCNTs (multiwall carbon nanotubes) and AC (activated ...

Multi-component catalysts are widely used to exploit the component interactions with the aim to improve catalysis processes. This study applies a model-aided approach to determine the optimal compositions of carbon nanotubes (CNTs) supported Pt-Co-Fe catalysts for selective hydrogenation of cinnamaldehyde. The methodology integrates an iterative response surface methodology (RSM) for optimizati...

The subject of this study was to optimize the transesterification parameters biodiesel produced from sword bean (C. gladiate) using Response Surface Methodology (RSM). Four (Reaction temperature 55 0C, Catalyst concentration 0.4 wt%, Methanol oil ratio 4:1 and reaction time 60 min) were optimized. Data obtained revealed that optimum conditions for C. gladiata seed resulted in 92.88% yield. Mult...

Conjugated linoleic acid (CLA) is one of the most physiological active fatty acids due to its positive effect on  prevention of diseases such as obesity, hyperlipidemia, atherosclerosis and cancer. The aim of this study was to optimize the production of conjugated linoleic acid (CLA)% in  alkali isomerization of safflower oil including  71% linoleic acid (LA)  using response surface methodology...