Electrospun nanofibrous structures provide good performance to scaffolds in tissue engineering. We measured the local diffusion coefficients of 3-kDa FITC-dextran in line patterns of electrospun nanofibrous structures fabricated by the direct-write electrospinning (DWES) technique using the fluorescence recovery after photobleaching (FRAP) method. No significant differences were detected betwee...

please cite this article as : tavakoli-darestani r, kazemian gh, emami m, kamrani-rad a. poly (lactide-co-glycolide) nanofibers coated with collagen and nano-hydroxyapatite for bone tissue engineering. novel biomed 2013;1:8-15. background: a combination of polymeric nanofibrous scaffold and bioactive materials is potentially useful in bone regeneration applications. materials and methods: in th...

poly vinyl alcohol/chitosan nanofibrous mat were prepared by electrospinning method with suitable pore sizes as potential matrices for soft tissue engineering. the designed scaffolds by electrospinning method evaluated by differentanalyses such morphological, mechanical, and cellular analysis.microscopic results showed diameters of poly vinyl alcohol/chitosan nanofibers were approximately 150 n...

introduction: the native inability of nervous system to regenerate, encourage researchers to consider neural tissue engineering as a potential treatment for spinal cord injuries. considering the suitable characteristics of induced pluripotent stem cells (ipscs) for tissue regeneration applications, in this study we investigated the adhesion, viability and proliferation of neural progenitors (de...

New-generation implants focus on robust, durable, and rapid tissue regeneration to shorten recovery times and decrease risks of postoperative complications for patients. Herein, we describe a new-generation thick nanofibrous implant functionalized with active containers of growth factors and stem cells for regenerative nanomedicine. A thick electrospun poly(ε-caprolactone) nanofibrous implant (...

Chondral and osteochondral defects affect a large number of people in which treatment options are currently limited. Due to its ability to mimic the natural nanofibrous structure of cartilage, this current in vitro study aimed at introducing a new scaffold, called XanoMatrix™, for cartilage regeneration. In addition, this same scaffold is introduced here as a new substrate onto which to study c...

The study aimed to fabricate and characterize a 2-part artificial cornea as a substitute for penetrating keratoplasty in patients with corneal blindness. The peripheral part of the artificial cornea consisted of plasma-treated electrospun poly (ɛ-caprolactone) (PCL) nanofibers, which were attached to a hydrogel disc of polyvinyl alcohol (PVA) as a central optical part. The physical properties o...