نتایج جستجو برای: nanometric membrane

تعداد نتایج: 390608  

Membrane permeability and P-glycoprotein (P-gp) efflux system are regulating factors in the drug brain penetration. Recently, some drug delivery systems have been developed to overcome these limitations. In this study, Metoclopramid has been encapsulated in PLGA nanoparticles using the emulsification/solvent evaporation technique for in vitro evaluation of the effect of PLGA nanoparticles on BB...

Membrane permeability and P-glycoprotein (P-gp) efflux system are regulating factors in the drug brain penetration. Recently, some drug delivery systems have been developed to overcome these limitations. In this study, Metoclopramid has been encapsulated in PLGA nanoparticles using the emulsification/solvent evaporation technique for in vitro evaluation of the effect of PLGA nanoparticles on BB...

Journal: :Circulation research 2012
Eva Wagner Marcel A Lauterbach Tobias Kohl Volker Westphal George S B Williams Julia H Steinbrecher Jan-Hendrik Streich Brigitte Korff Hoang-Trong M Tuan Brian Hagen Stefan Luther Gerd Hasenfuss Ulrich Parlitz M Saleet Jafri Stefan W Hell W Jonathan Lederer Stephan E Lehnart

RATIONALE Transverse tubules (TTs) couple electric surface signals to remote intracellular Ca(2+) release units (CRUs). Diffraction-limited imaging studies have proposed loss of TT components as disease mechanism in heart failure (HF). OBJECTIVES Objectives were to develop quantitative super-resolution strategies for live-cell imaging of TT membranes in intact cardiomyocytes and to show that ...

Journal: :iranian journal of pharmaceutical research 0
niusha nikandish nano drug delivery research center, kermanshah university of medical sciences, kermanshah, iran leila hosseinzadeh department of toxicology and pharmacology, faculty of pharmacy, kermanshah university of medical sciences, kermanshah, iran katayoun derakhshandeh department of pharmaceutics, school of pharmacy, kermanshah university of medical sciences, kermanshah , iran abbas hemmati azandaryani departmant of applied chemistry, faculty of chemistry, razi university, kermanshah, iran

membrane permeability and p-glycoprotein (p-gp) efflux system are regulating factors in the drug brain penetration. recently, some drug delivery systems have been developed to overcome these limitations. in this study, metoclopramid has been encapsulated in plga nanoparticles using the emulsification/solvent evaporation technique for in vitro evaluation of the effect of plga nanoparticles on bb...

Journal: :Nanotechnology 2011
B Lebental P Chainais P Chenevier N Chevalier E Delevoye J-M Fabbri S Nicoletti P Renaux A Ghis

Structural health monitoring of porous materials such as concrete is becoming a major component in our resource-limited economy, as it conditions durable exploitation of existing facilities. Durability in porous materials depends on nanoscale features which need to be monitored in situ with nanometric resolution. To address this problem, we put forward an approach based on the development of a ...

2014
Yu. M. Yevdokimov V. I. Salyanov E. V. Shtykova N. G. Khlebtsov E. I. Kats S. G. Skuridin

Two different approaches to the creation of “rigid” (gel-like) DNA particles (or DNA nanoconstructions) are considered. The physicochemical approach is based on the formation of nanobridges between double-stranded DNA molecules ordered in quasinematic layers of cholesteric liquid-crystalline dispersion (CLCD) particles or their salting-out. This approach represents by itself a “chemical gelatio...

Journal: :Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2007
Vincenzo Palermo Andrea Liscio Anna Maria Talarico Linjie Zhi Klaus Müllen Paolo Samorì

Synthetic nanographenes have been self-assembled from solution on the surface of nanometric channels of an alumina membrane template. By controlling the interplay between intermolecular and interfacial interactions, the molecules have been adsorbed either 'face-on' or 'edge-on' on the pore's surfaces, leading to the formation of columnar stacks in the latter case. Upon thermal treatment at high...

Journal: :Chemical communications 2008
Aldo Arrais Mauro Botta Stefano Avedano Giovanni Battista Giovenzana Eliana Gianolio Enrico Boccaleri Pier Luigi Stanghellini Silvio Aime

Novel sub-microsized graphitic carbon shells embedding nanometric Gd(III) oxidic phases feature thermal and chemical inertness with enhanced T2 relaxation in aqueous dispersions, thus representing potential candidates for dual diagnostic (magnetic resonance imaging) and therapeutic (neutron capture therapy) applications.

2010
Robert A. Varin Marek Polanski

The recent advances on the effects of microstructural refinement and various nano-catalytic additives on the hydrogen storage properties of metal and complex hydrides obtained in the last few years in the allied laboratories at the University of Waterloo (Canada) and Military University of Technology (Warsaw, Poland) are critically reviewed in this paper. The research results indicate that micr...

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