Background: Vitiligo is a pigmentation disorder of the skin characterized by the loss of melanocytes through different mechanisms. Narrow band UVB (NBUVB) is a safe and effective treatment for vitiligo that acts by inducing the synthesis of cytokines involved in melanogenesis. NBUVB appears to be involved in the treatment of vitiligo by increasing the synthesis of vitamin D, which prevents the ...

Background. Psoriasis impairs the quality of life (QoL) of patients as is in such severe diseases as cardiac failure or some malignant diseases. The aim of the study was to assess the QoL of Bulgarian psoriasis patients and its dynamics after different treatment approaches. Matherial and methods. The study was conducted in 93 patients (55 men and 38 women), mean age 45 years. The patients were ...

Objective: Various topical agents block UVB penetration when applied before UVB therapy. The effects of topically used erythromycin and tetracycline on narrow band UVB has not been considered yet. We investigated the effects of topically used erythromycin 2%, erythromycin 4% and tetracycline on the penetration amount of narrow band UVB. Methods: In this study 32 patients without any photodermat...

Vitiligo is one of the skin diseases where there a disorder in pigmentation (skin color disorder), which characterized by presence macula hypopigmentation (a condition that causes part to become lighter than surrounding color) caused loss melanocyte function special cell found under epidermis functions produce pigments/melanin) chronically and progressively from epidermis. This disease if left ...

Psoriasis is a chronic inflammatory skin disease. Metabolic syndrome (MS) is a combination of central obesity, dyslipidemia, glucose intolerance, and elevated blood pressure. Many epidemiological surveys have revealed the association of psoriasis with MS. Narrowband ultraviolet radiation b (NB-UVB) is an effective and widely used treatment for psoriasis. The purpose of this study was to investi...

Psoriasis is more common among patients with obesity. These patients tend to have more severe psoriasis. Therefore, a higher proportion of them require intensive treatment modalities such as phototherapy, but with not always dose adjustment. We report a phototherapy-induced erythema in patient with psoriasis and obesity treated with narrowband UVB phototherapy. Figure 1: Erythema located on the...

Ultraviolet B (UVB) phototherapy is a safe and effective treatment for moderate to severe psoriasis. UVB treatment typically requires patients to visit an outpatient clinic two to three times per week during business hours, a schedule which can be impractical for some individuals. Depending on a patient's insurance coverage, outpatient phototherapy can be expensive. In these situations, home UV...

BACKGROUND Very few studies have been performed to evaluate the efficacy and safety of narrow-band ultraviolet B (NBUVB) therapy in Indian patients with vitiligo and are of small sample size. AIMS The purpose of this study is to know the efficacy and safety of NBUVB in 150 vitiligo patients of various age groups. METHODS One hundred fifty patients (69 males, 81 females), aged 3-70 years, wi...

UNLABELLED Narrowband ultraviolet B (NB-UVB) phototherapy, with a 308-nm xenon chloride excimer laser, and targeted UVB phototherapy have produced encouraging therapeutic results for vitiligo. However, very few studies employing broadband UVB exist. Moreover, there has been no direct comparison study between broadband UVB and NB-UVB for the treatment of vitiligo. The aims of this study were to ...