This review covers some of the opportunities which currently exist to exploit plants for their natural products as templates for new antibacterial substances. This is a timely exercise given the continuing and developing problems of bacterial resistance, and in particular multidrug-resistance (MDR). Some of the challenges which are evident with bacterial resistance will be described and the str...

Antibacterial activity of the aerial extracts from Xanthium brasilicum prepared in methanol, diethyl ether, petroleum benzene and an equal mixture of the three solvents were studied against bacterial laboratory standards and clinical isolates using the disk diffusion method. The best antibacterial results were obtained when methanol or the solvent mixture was used. The crude extract with the hi...

Lactic acid bacteria (LAB) isolated from various foods are important due to their potential to inhibit microorganisms, including drug-resistant bacteria. The objectives of this investigation were to isolate and identify antibacterial substances producing LAB from Hentak, a traditional fermented fish product of Manipur (North-East India), and to optimize the production of antagonistic substances...

Antibacterial activity of the aerial extracts from Xanthium brasilicum prepared in methanol, diethyl ether, petroleum benzene and an equal mixture of the three solvents were studied against bacterial laboratory standards and clinical isolates using the disk diffusion method. The best antibacterial results were obtained when methanol or the solvent mixture was used. The crude extract with the hi...

Two strains, HG104 and ASSO, were isolated Crom the soil of Tehran's suburbs. Taxonomic studies showed thatHG104 and AS50 belong to Mycobacterium spp. and Brevibacterium spp. respectively, which produce antibacterial substances with relatively high activity against some important clinical Gram-positive and Gramnegative bacteria

Secondary metabolites of the marine sponges Acanthella elongata, Axinella donnani, Callyspongia diffusa, Callyspongia subarmigera, and Echinodictyum gorgonoides were collected from fishing nets and their in vitro antibacterial properties against eight virulent marine fish pathogens were studied at incubation temperatures of 20°C and 30°C. Crude methanol extracts of the tested sponges showed spe...

Background: Identifying the best species of medicinal plants and extracting effective substances can be effective in preventing oral and dental illness. The Malva sylvestris L. is among these plants. Malva sylvestris L. belongs to Malvaceae family from which A great deal of (Malvone A: 2-methyl-3-methoxy-5,6-di- hydroxy-1,4-naphthoquinone) anthocyanin and important natural pigments have been ex...

Drug design is a complex issue that still lack general approach with proven reliability. Combinatorial chemistry and HTS techniques did not appear to be effort-effective. As an alternative we have the fragment based design and more recently so called the privileged structures approach. We believe that some structural subunits are especially effective in design of bioeffectors. However it is not...

Species of the genus Elsholtzia have great potential for bioactive substances. Although this species has been used a lot in traditional medicines, most it is only based on experience gained or left by forerunners without much knowledge scientific basis. Therefore, investigation, research, evaluation chemical composition and screening substances from plants Elsholtzia, especially those endemic t...

Over the past few decades there has been much interest in natural materials as sources of new antibacterial agents. Different extracts from traditional medicinal plants have been tested. Many reports show the effectiveness of traditional herbs against microorganisms; as a result, plants have become one of the bases of modern medicine (Evans et al., 2002). Plants have given the Western pharmacop...