During embryogenesis, brain neurons receiving the same sensory input may undergo potentiation or depression. While the origin of variable plasticity in vivo is unknown, it plays a key role in shaping dynamic neural circuit refinement. Here, we investigate effects of natural visual stimuli on neuronal firing within the intact, awake, developing brain using calcium imaging of 100 s of central neu...

we investigated the association between serum 25(oh) d levels and depressive symptoms in patients with major depressive disorder (mdd).eighty-five adults, 44 drug free patients with mdd and 41 apparently healthy controls, participated in the study. the hamilton depression rating scale was used to assess severity of major depression. mental health of the controls was assessed according to dsm-iv...

Major depressive disorder (MDD) is a prevalent psychiatric condition that results in persistent feelings of sadness and loss interest, imposing significant economic burden on health systems society. Impaired sleep both symptom risk factor for depression. Natural astaxanthin (AST), carotenoid primarily derived from algae aquatic animals, possesses multiple pharmacological properties such as anti...

Depression is a well-known co-morbidity in heart failure. In fact, approximately half of all patients with heart failure suffer from signs of depression. Co-morbid depression severely worsens prognosis in these patients. However, the majority of these patients remain untreated; beside the point that the cardiologist regards depression often as a “natural” response on a life threatening conditio...

objective: environmental psychology as a science could be useful in understanding the dissociation between the man and the environment. the aim of this study was to compare mental health, job satisfaction and well-being of nurses who work in hospital environments with different designs. material: this was a quasi-experimental study, in which 250 nurses filled out the mental health, well-being a...

An increasingly large body of work in adults has shown that derangements in the immune system, a critical protector from disease, are associated with stress, bereavement, and depression (for review, see Schleifer et al 1986, Calabrese et al 1987). We (Kronfol et al 1989) and others (Mohl et al 1987; Nerozzi et al 1989; Irwin et al 1990) have reported lower natural killer (NK) cell activity, a p...

The use of herbs or their parts: leaves, roots, rhizomes, flowers, seeds, natural strains, as well as extracts or isolated metabolites is becoming more and more popular. Natural remedies not only act prophylactically, but also help to alleviate symptoms of many diseases and enhance the overall functioning of the internal organs. Many raw materials of natural origin plays a role in treatment of ...

Proxy measures of genome-wide heterozygosity based on approximately 10 microsatellites have been used to uncover heterozygosity fitness correlations (HFCs) for a wealth of important fitness traits in natural populations. However, effect sizes are typically very small and the underlying mechanisms remain contentious, as a handful of markers usually provides little power to detect inbreeding. We ...

Depression presents in roughly 20% of people with diabetes worldwide, and adversely affects quality of life and treatment outcomes. The causes of depression in diabetes are poorly understood, but research suggests a bi-directional association, at least for type 2 diabetes. Inconsistent findings regarding prevalence and depression treatment outcomes in patients with diabetes seem partly attribut...