Angiogenesis is the formation of new blood vessels which is a key part of tumor growth and spread. New blood vessels convey nutrients to the cancer, fueling their abnormal growth and metastasis. The first successful antiangiogenic inhibitor interferon alfa2a has been used for the treatment of pulmonary hemangiomatosis in 1989. Tumors cannot grow or spread without the formation of new blood vess...

Natural products as pesticides have been reviewed from several perspectives in the past, but no prior treatment has examined the impact of natural product and natural product-based pesticides on the U.S. market, as a function of new active ingredient registrations with the Environmental Protection Agency (EPA). Thus, EPA registration details of new active ingredients for all conventional pestic...

Natural products used as food or drinks, clues from the fascinating science of zoopharmacognosy, terrestrial animals and their excreta, and many other NPs not primarily known for their medical use, seem to have, to a great extent, escaped the attention of natural product research. It is nevertheless highly probable that these sources could contain biologically active compounds, some of which wi...

Europa’s interior structure may be determined by relatively simple and robust seismo-acoustic echo sounding techniques. The strategy is to use ice cracking events or impacts that are hypothesized to occur regularly on Europa’s surface as sources of opportunity. A single passive geophone on Europa’s surface may then be used to estimate the thickness of its ice shell and the depth of its ocean by...

We present a preliminary survey of 58 radio sources within the isoplanatic patches (r < 25′′) of bright (11 < R < 12) stars suitable for use as natural guide stars with high-order adaptive optics (AO). An optical and near-infrared imaging survey was conducted utilizing tip-tilt corrections in the optical and AO in the near-infrared. Spectral Energy Distributions (SEDs) were fit to the multiband...

Synthetic hormones and bioactive substances (vitamins, pigments and isoflavons) which have been used in the feed industry are accumulated in milk, meat and eggs. It is suspected that these are responsible for a number of side-effects such as carcinogenesis, liver and kidney damage, allergies in consumers. Furthermore the synthetic hormones, vitamins, pigments are less active than those extracte...