canine ehrlichiosis has emerged as one of the most clinically important tick-borne diseases affecting dogs. eighty-five naturally infected dogs have been investigated, the most consistent clinical signs recorded were fever, emaciation and lymphoadenopathy, anemia, monocytosis, thrompocytopenia, hypoalbuminemia, elevation in liver enzymes and total bilirubin were the most remarkable changes asso...

Asbestos is a ubiquitous naturally occurring fiber causing multiple cancers and fibroproliferative disease. The mechanisms of epithelial cell hyperplasia, a hallmark of the initiation of lung cancers by asbestos, have been unclear. We demonstrate here that mice expressing a dominantnegative mutant epidermal growth factor receptor (EGFR) under the control of the human lung surfactant protein-C p...

Asbestos is a lethal and naturally occurring group of minerals that has brought death and misery to people worldwide. Due to its good tensile strength and resistance to damage, asbestos became extremely popular throughout the early 20th century, and, in many less wealthy nations, remains so today, where it has several uses including strengthening cement and prolonging the life of road surfaces....

Enolethers are a group of reactive compounds also occurring in the nature and displaying different kinds of activities, such as antifungal, antibacterial, nematocidal, cytostatic, cytotoxic, phytotoxic, nematicidal, antipyretic, hypotensive, analgesic, antitussive, depresant, anticancerogenic and antiviral.

RATIONALE Little is known about environmental exposure to low levels of naturally occurring asbestos (NOA) and malignant mesothelioma (MM) risk. OBJECTIVES To conduct a cancer registry-based case control study of residential proximity to NOA with MM in California. METHODS Incident MM cases (n = 2,908) aged 35 yr or more, diagnosed between 1988 and 1997, were selected from the California Can...

Naturally occurring asbestos (NOA) fibers are found in geologic deposits that may be disturbed by mining, earthworks, or natural processes, resulting in adverse health risks to exposed individuals. The toxicities of Libby amphibole and NOA samples including Sumas Mountain chrysotile (SM), El Dorado tremolite (ED), and Ontario ferroactinolite cleavage fragments (ON) were compared in male Fischer...

Although many foods contain toxins as a naturally-occurring constituent or, are formed as the result of handling or processing, the incidence of adverse reactions to food is relatively low. The low incidence of adverse effects is the result of some pragmatic solutions by the US Food and Drug Administration (FDA) and other regulatory agencies through the creative use of specifications, action le...

Wollastonite is a naturally occurring acicular or fibrous metasilicate used in ceramics and as a substitute for asbestos in some applications. Wollastonite fibers are rather similar in form, length, and diameter to amphibole asbestos fibers but mineralogically they are different. Dust measurements in both the Finnish limestone--wollastonite quarry and in the flotation plant yielded high concent...