Vitiligo is a common, acquired pigmentary disorder of unknown pathogenesis that presents a therapeutic challenge to many dermatologists (Figure 1). Although surgery in the form of grafting or transplantation is generally the most definitive treatment option, these procedures are limited by concerns of post-procedure cosmesis. Photochemotherapy using psoralen and ultraviolet A (PUVA) therapy, to...

LTA: lymphocytic thrombophilic arteritis MLA: macular lymphocytic arteritis NBUVB: narrow-band ultraviolet B INTRODUCTION Macular lymphocytic arteritis (MLA) and lymphocytic thrombophilic arteritis (LTA) are terms used to describe an indolent, cutaneous medium-vessel vasculitis that has been suggested to follow a benign but persistent disease course. Pathologically, this condition is characteri...

Background: Treatment of vitiligo remains an attractive topic and several therapies with varying degrees of success have been used. The aim of this study was to find out whether the combination of topical calcipotriol and excimer laser increases the efficacy of therapy compared to excimer laser alone. Methods: Twenty eight patients in two groups were treated with 308nm excimer laser alone (14 p...

Mục tiêu: Mô tả triệu chứng lâm sàng và đánh giá kết quả điều trị bệnh vảy nến thông thường thể mảng bằng tia cực tím B dải hẹp. Đối tượng phương pháp nghiên cứu: Nghiên cứu 40 nhân được hẹp tại viện da liễu trung ương từ tháng 6/2018 đến 7/2019. Kết quả: 27 nam chiếm tỷ lệ 67.5%, 13 nữ 31,5%. Vị trí tổn thương hay gặp nhất là ở thân mình 100%, trên đầu 92,5%. Mức độ của nhóm đối chủ yếu mức bì...

Background The anti-programmed cell death-1 (PD-1) and anti-programmed cell death ligand-1 (PD-L1) immunotherapies have shown exceptional activity in many cancers. However, these immunotherapies can also result in diverse adverse cutaneous eruptions that need to be better characterized for ongoing management. The objective was to provide clinical and histopathologic descriptions of the variety ...

Background: Psoriasis is a chronic inflammatory skin disease that is estimated to affect 0.6% to 4.8% of the general population. The optimum number of NB-UVB phototherapy sessions is yet to be determined. The aim of this study was to compare therapeutic effects of NB-UVB in treating chronic plaque type psoriasis three times weekly vs. five times weekly. Materials and Methods: This study was des...

In repigmentation of human vitiligo, the melanocyte (MC) precursors in hair follicle bulge proliferate, migrate, and differentiate to repopulate depigmented epidermis. Here, we present a comprehensive characterization pathways signals that control process. Using biopsies from patients with have selectively harvested, by laser capture microdissection, MC keratinocyte untreated vitiligo skin trea...

Introduction: Mogamulizumab (moga) is an anti-CCR4, monoclonal antibody approved as monotherapy for the treatment of relapsed/refractory mycosis fungoides (MF) and Sezary syndrome (SS). Combination therapies are frequently utilized in cutaneous T-cell lymphoma (CTCL), part due to variation response across blood, nodal, skin compartments. Little known about moga combination with other therapies....