We present a 42-year-old woman with no history of diabetes or glucose intolerance who had a 5-year history of ulcerative necrobiosis lipoidica (NL). Despite failure of multiple medications, she experienced clearing of her ulcers after her treatment was changed to ustekinumab. We discuss our patient's disease course and elaborate upon mechanistic reasons for her improvement related to ustekinuma...

5. Van Esso DL. Los padres frente a la vacunación. Vacunas. 2010;11:133--4. 6. Jiménez Gómez N, Ballester Martínez MA, Alcántara González J, Jaén Olasolo P. Koplik spots as a diagnostic clue in a case of measles. Med Clin (Barc). 2012;139:560. 7. Lefebvre N, Camuset G, Bui E, Christmann D, Hansmann Y. Koplik spots: a clinical sign with epidemiological implications for measles control. Dermatolo...

A 56-year-old Caucasian male with a history of uncontrolled diabetes mellitus and multiple other comorbidities was evaluated for slowly expanding plaques of his right lower leg, left forearm and left dorsal hand that had been present for the past six years. The patient denied any associated pruritus or pain. There was no history of previous trauma, immunosuppression, recent travel or prior trea...

BACKGROUND Diabetes mellitus (DM) is a clinical syndrome characterized by hyperglycaemia due to absolute or relative insulin deficiency. The aim of this study was to evaluate the frequency of skin manifestations in patients with diabetes mellitus of this area. This descriptive study was conducted in medical out patient door of District Headquarter Hospital Battgram from January 2008 to July 200...