Newer parts of sex chromosomes, neo-sex chromosomes, offer unique possibilities for studying gene degeneration and sequence evolution in response to loss of recombination and population size decrease. We have recently described a neo-sex chromosome system in Sylvioidea passerines that has resulted from a fusion between the first half (10 Mb) of chromosome 4a and the ancestral sex chromosomes. I...

Previously this laboratory characterized Slc39a8-encoded ZIP8 as a Zn(2+)/(HCO(3)(-))(2) symporter; yet, the overall physiological importance of ZIP8 at the whole-organism level remains unclear. Herein we describe the phenotype of the hypomorphic Slc39a8(neo/neo) mouse which has retained the neomycin-resistance gene in intron 3, hence causing significantly decreased ZIP8 mRNA and protein levels...

The last twenty years or so have seen a lot of discussion about systematicity-roughly the idea that if a person's repertoire contains the sentence/thought thatJohn loves Mary, then her repertoire also contains the sentence/thought that Mary loves John.' Much of the discussion of systematicity has focused on the technical question of whether and how connectionists can explain the systematicity o...

OBJECTIVES We sought to assess the prevalence and progression of neo-aortic root dilation and valvar regurgitation after staged reconstruction for hypoplastic left heart syndrome (HLHS). BACKGROUND In HLHS, the pulmonary valve functions as the neo-aortic valve. Neo-aortic valve dysfunction has been observed after arterial switch operation and the Ross procedure. METHODS Patients with HLHS b...

It is offered here a Spanish translation of the Φιλοοπλάηων, with introduction, notes and interpreting commentary; it highlighted that this work represents genre satura in Byzantium, according to large tradition assumed by 'classicism' XIIth century, represented also Ἀμαθής, Καηὰ θιλοπόρνοσ γραός μακρογενείοσ γέρονηος; these works have similarities Φιλοπλάηων.