نتایج جستجو برای: neurodegenerative diseases

تعداد نتایج: 865792  

2011
Quan Liu Fang Xie Abdiel Alvarado-Diaz Mark A Smith Paula I Moreira Xiongwei Zhu George Perry

Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration. In this review, the most recent discovery and central arguments about functions, pathological m...

Fatemeh Alipour, Maryam Borhani-Haghighi,

Microglia is a type of glial cell located throughout the central nervous system (CNS), which is sensitive to CNS injury and disease. Responsibility of microglia as the resident macrophage cells for injuries suggests that these cells have the potential to act as diagnostic markers of disease beginning or progression. Function of Microglia is strongly synchronized by the microenvironment of brain...

ژورنال: ارمغان دانش 2019

Abstract Background & aim: Kynurenine pathway (KP) plays an important role in the pathogenesis of neuroinflammation and neurodegenerative disorders. In neurodegenerative diseases (NDD) such as Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD) and Multiple sclerosis (MS), brain neurons are initially involved and gradually disappear. In the present review article, the ...

Journal: :Trends in Molecular Medicine 2009

Journal: :International Journal of Cell Biology 2014

Journal: :World Journal of Clinical Cases 2015

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