Between ages 4 and 6, children become better at inferring what others are thinking and feeling. However, the neural correlates of these advances are understudied. The current study investigated the relation between performance on a face-based mental state inference task and white matter characteristics. Two tracts of interest, the uncinate fasciculus (UF) and inferior longitudinal fasciculus, w...

Recent resting-state functional MRI investigations have demonstrated that much of the large-scale functional network architecture supporting motor, sensory and cognitive functions in older pediatric and adult populations is present in term- and prematurely-born infants. Application of new analytical approaches can help translate the improved understanding of early functional connectivity provid...

Copy number variations (CNVs) consist of duplications or deletions of chromosomal regions ranging from a few hundred to more than a million bases in size, and are likely to play a role in phenotypic diversity and evolution. Recent advances in the identification and mapping of CNVs among normal individuals and in model systems, using bioinformatics and hybridization-based methods, are beginning ...

"Children are not resilient, children are malleable." RESILIENT 1. Marked by the ability to recover readily, as from misfortune. 2. Capable of returning to an original shape or position, as after having been compressed. MALLEABLE 1. Capable of being shaped or formed, as by hammering or pressure: a malleable metal. 2. Easily controlled or influenced; tractable. 3. Able to adjust to changing circ...

The neurodevelopmental hypothesis of schizophrenia provided a valuable framework that allowed a condition that usually presents with frank disorder in adolescence or early adulthood to be understood at least in part as a consequence of events occurring early in development. However, the implications of the neurodevelopmental hypothesis for nosological conceptions of the disorder can only now be...

Sleep disorders in children are among the most common parental complaints to health care professionals and frequently occur in children with neurological and developmental disorders. Thus, I am grateful to the editors of Neuropediatrics for the opportunity to assemble in one place several papers that outline the contemporary knowledge about sleep disorders in patients with neurodevelopmental di...