For the past decade, neuroendocrinology, in general, and neuroendocrine regulation of reproduction, in particular, were strongly dominated by molecular genetics and molecular endocrinology. In very recent years, however, neuroendocrinology is taking back its place. Beyond doubt GnRH is the neuroendocrine signal for ovulation. But there are still many unexplored pathways within the 'black box' t...

Natural selection has linked the physiological controls of energy balance and fertility such that reproduction is deferred during lean times, particularly in female mammals. In this way, an energetically costly process is confined to periods when sufficient food is available to support pregnancy and lactation. Even in the face of abundance, nutritional infertility ensues if energy intake fails ...

Selected reptilian species have been the targets of investigations in behavioral neuroendocrinology for many years. Reptiles offer a particularly powerful set of traits that facilitate comparisons at multiple levels, including those within and between individuals of a particular species, between different environmental and social contexts, as well as across species. These types of studies, part...

1 Department of Psychology and Neuroscience, Baylor University, Waco, TX, USA, 2 Department of Affective Psychology, Institute of Psychology, Eötvös Loránd University, Budapest, Hungary, 3 Department of Affective Psychology, Doctoral School of Psychology, Eötvös Loránd University, Budapest, Hungary, 4 Laboratory of Molecular Neuroendocrinology, Institute of Experimental Medicine, Budapest, Hung...

A. A. AMMAR,1* F. SEDERHOLM,1* T. R. SAITO,2* A. J. W. SCHEURINK,3 A. E. JOHNSON,1 AND P. SÖDERSTEN1 1Section of Applied Neuroendocrinology, Karolinska Institutet, Novum, S-141 57 Huddinge, Sweden; 2Division of Veterinary Ethology, Department of Laboratory Animal Sciences, Nippon Veterinary and Animal Science University, Musashino-shi, Tokyo 180, Japan; and 3Department of Animal Physiology, Uni...

It seems amazing that a research worker as prolific as Dr. Michelson should have been able to find time to write this excellent volume with its more than two thousand references. It is admirable that a publisher should be able to print a book in 1963 in which so many late 1962 references are included. The degree of completeness with which the organic and physical chemistry of nucleosides, nucle...

the analyses of kinetic patterns, and the physical-chemical theories of enzyme action are discussed in the first section. The second section is devoted to a detailed kinetic analysis of two substrate reactions under steady state conditions. The methods by which experimental variations of pH and temperature may be coupled with other types of kinetic analyses to yield information on the mechanism...

G protein-coupled receptors (GPCRs) represent the single largest family of plasma membrane receptors, encompassing about 860 members in humans. During the last decades, considerable progress has been made regarding the biochemical identification, signaling mechanisms, allosteric modulation, structural characterization, and pathophysiological implication of GPCRs, which are considered as major t...