نتایج جستجو برای: neuron like cells

تعداد نتایج: 1967951  

عبدانی پور, علیرضا, قلی نژاد, معصومه, نیک فر, علی,

Background and Objective: Damaged and inflammatory cells in the nervous system produce reactive oxygen species (ROS). The overproduction of ROS can cause serious damage to important biomolecules and over activation of programmed cell death leads to many progressive neurodegenerative disorders. The aim of this study was to evaluate the effects of selegiline on inhibition of apoptosis in oxidativ...

Journal: :International journal of molecular medicine 2012
Te Liu Zhangbin Gong Lengchen Hou Yongyi Huang

Parkinson's disease (PD) is a widespread age-associated neurodegenerative disorder. Current treatment is symptomatic rather than curative. However, stem cell replacement therapies may have the potential to offer curative treatment. In this study, we demonstrate that rat CD49f+ spermatogonial stem cells (rSSCs) can be induced to become functional dopaminergic neuron-like cells in vitro. Furtherm...

Journal: Nanomedicine Journal 2019

Objective(s): The present study was designed to evaluate of Metformin/Irinotecan-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles (NPs) effects on glutamate re-uptake time and receptor expression status in both glioblastoma multiforme (GBM) and cortex neuron cultures. The study was performed on glioblastoma cell line and primer cortex neuron.Materials and Methods: The re-uptake time and...

2013
Shahrul Hisham Zainal Ariffin Shabnam Kermani Intan Zarina Zainol Abidin Rohaya Megat Abdul Wahab Zulham Yamamoto Sahidan Senafi Zaidah Zainal Ariffin Mohamad Abdul Razak

Dental pulp tissue contains dental pulp stem cells (DPSCs). Dental pulp cells (also known as dental pulp-derived mesenchymal stem cells) are capable of differentiating into multilineage cells including neuron-like cells. The aim of this study was to examine the capability of DPSCs to differentiate into neuron-like cells without using any reagents or growth factors. DPSCs were isolated from teet...

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