Butane-2,3-dione was activated towards nucleophilic addition of enecarbamates by a series of metal triflate complexes of a C2-symmetric diamine to give stereogenic, aldol-like, t-alcohols, a novel nickel(II) triflate complex was identified as a good catalyst for this asymmetric transformation, and an aquo nickel(II) complex was identified by XRD techniques.

Background: Heavy metals in aquatic systems usually interfere with many beneficial uses of water. Divalent nickel is a commonly occurring toxic metal in natural ecosystems due to the effluent of refineries, electroplating, and casting industries. In aquatic environments, nickel appears as Ni (II) and Ni0. Despite the high reported toxicity for Ni (II), Ni0 is only slightly toxic. Various meth...

Our research group have been working on transistion metal complexes and their activity in the biology field, especially antimicrobial and anticancer properties. Novel pseudohalide ligands with orotic acid and its metal salt Ni(II) have been synthesized and evaluated for their antimicrobial activities by disc diffusion method. The complexes have been characterized by IR, SEM, Raman, P-Xrd and UV...

Citation: Frontiers Editorial Office (2016) Expression of Concern: Mechanism of Action of the Novel Nickel(II) Complex in Simultaneous Reactivation of the Apoptotic Signaling Networks Against Human Colon Cancer Cells. Front. Pharmacol. 7:190. doi: 10.3389/fphar.2016.00190 Expression of Concern: Mechanism of Action of the Novel Nickel(II) Complex in Simultaneous Reactivation of the Apoptotic Sig...

Nickel has been shown to be an essential trace element involved in the metabolism of several species of bacteria, archea, and plants. In these organisms, nickel is involved in enzymes that catalyze both non-redox (e.g., urease, glyoxalase I) and redox (e.g., hydrogenase, carbon monoxide dehydrogenase, superoxide dismutase) reactions, and proteins involved in the transport, storage, metallocente...

In the present paper, a solid phase extraction system for separation and preconcentration of nickel (ng g(-1)) in saline matrices is proposed. It is based on the adsorption of nickel(II) ions onto an Amberlite XAD-2 resin loaded with 1-(2-pyridylazo)-2-naphthol (PAN) reagent. Parameters such as the pH effect on the nickel extraction, the effect of flow rate and sample volume on the extraction, ...

Nickel-catalyzed [3 + 2] cycloaddition of 2-trifluoromethyl-1-alkenes with alkynes via domino C-F bond activation was achieved by sequential β-fluorine elimination. The nickel(ii) fluoride species formed in this reaction was reduced by a diboron compound, regenerating the catalytically active nickel(0) species.

A sensitive, selective and rapid method for the determination of nickel based on a rapid reaction of nickel(II) with 2-(2-quinolylazo)-5-diethylaminoaniline (QADEAA) has been developed. In the presence of pH = 6.0 ammonia-ammonium chloride buffer solution and sodium dodecyl sulfonate (SDS) medium, QADEAA reacts with nickel to form a violet complex having a molar ratio of 1:2 (nickel to QADEAA)....

Helicobacter pylori NikR (HpNikR) is a nickel-dependent transcription factor that regulates multiple genes in the H. pylori pathogen. There are conflicting data regarding the locations of the Ni(II) sites and the role of Ni(II) coordination in DNA recognition. Herein, we report crystal structures of (i) the metal-binding domain (MBD) of HpNikR (3.08 Å) and (ii) a mutant, H74A (2.04 Å), designed...