Pathways of mannitol biosynthesis and utilization in Aspergillus candidus NRRL 305 were studied in cell-free extracts of washed mycelia prepared by sonic and French pressure cell treatments. A nicotinamide adenine dinucleotide-linked mannitol-1-phosphate (M1P) dehydrogenase was found in French pressure cell extracts of d-glucose-grown cells, whereas a specific mannitol-1-phosphatase was present...

UNLABELLED There is some evidence of a relationship between nitric oxide and pain control pathways. However, it is still controversial whether nitric oxide synthase (NOS) inhibitors affect minimum alveolar anesthetic concentration (MAC). We examined the effects of 7-nitro indazole (7-NI), a selective neuronal NOS (nNOS) inhibitor, on halothane MAC. With nicotinamide adenine dinucleotide phospha...

Isolated corn (Zea mays L.) mitochondria were found to oxidize reduced nicotinamide adenine dinucleotide phosphate in a KCl reaction medium. This oxidation was dependent on the presence of calcium or phosphate or both. Strontium and manganese substituted for calcium, but magnesium or barium did not. The oxidation of NADPH produced contraction of mitochondria swollen in KCl. Further evidence tha...

3-NPA 3-nitropropionic acid ADP adenosine diphosphate AKT protein kinase B AMP adenosine monophosphate AMPK adenosine monophosphate-activated protein kinase AP-1 activator protein 1 ATP adenosine triphosphate CAT catalase ERK extracellular signal regulated kinase FADH flavin adenine dinucleotide FOX forkhead box FOXO O class forkhead box GPx glutathione peroxidase GST glutathione S-transferase ...

A possible alternate vital role of the structural gene for reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase in Aspergillus nidulans was tested for and found to be absent in a significant number of haploid and diploid strains.

The fluorescence of a fermentation culture was studied for its application as an estimator of biomass concentration. The measurement was obtained by irradiating the culture with ultraviolet light (366 nm) through a glass window and detecting fluorescent light at the window surface at 460 nm. It was estimated that over one-half of the fluorescent material was intercellular reduced nicotinamide a...

1. The inducible p-hydroxybenzoate hydroxylase of Pseudomonas putidu which catalyzes the hydroxylation of P-hydroxybenzoate to protocatechuate has been obtained in crystalline form as a protein homogeneous upon ultracentrifugation and electrophoresis. The molecular weight is estimated to be 83,600. 2. The enzyme contains approximately 1 mole of flavin adenine dinucleotide per mole of protein. R...

Chloroplasts photochemically reduce 1,1'-trimethylene-2,2'-dipyridylium dibromide and concurrently form adenosine triphosphate. Reduced trimethylene dipyridyl in darkness will reduce spinach ferredoxin, Clostridium pasteurianum ferredoxin, nicotinamide-adenine dinucleotide phosphate, and other viologen-type dyes.