conclusions decreases in the serum levels of liver aminotransferases and cytokines, in both groups, are related to low-calorie diets and exercise, rather than ptx. results the serum levels of liver aminotransferases were significantly reduced at 3 months and at 6 months, compared with baseline, in both groups. the serum levels of il-6 were significantly decreased, in both groups, only at 6 mont...

In article number 2007425, Junmin Lee, Ali Khademhosseini, and co-workers present a breakthrough for modeling of non-alcoholic fatty liver disease (NAFLD) based on bioengineered multicellular microtissues liver-on-a-chip system. The consisting four major cell types (primary human hepatocytes, stellate cells, Kupffer endothelial cells) recapitulate the pathogenesis hepatic fibrosis driven by NAF...

Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most important causes liver disease worldwide leading foreground cause transplantation. Recently miRNAs, small non-coding molecules were identified as an player in negative translational regulation many protein-coding genes involved hepatic metabolism. Visceral adipose tissue was found to take part lipid and glucose metabolism release infl...

Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in Western countries in which men and women are affected equally (de Alwis and Day 2008; Willner et al. 2001). The prevalence and severity of NAFLD increase with obesity (Flegal et al. 1998 & 2003). Since obesity is known to have a genetic etiology, we propose that genetic factors influence susceptibility...

Background and objectives: Non-alcoholic fatty liver disease (NAFLD) is a common liver condition. On the other hand, coffee consumption has shown promising for gastrointestinal diseases.  Detection of the most valuable biomarkers of decaffeinated coffee treatment in healthy and non-alcoholic fatty liver disease conditions was the aim of the present study. Methods:</stro...

background: omega-3 fatty acids have established beneficial effects for cardiovascular disease. the use of omega-3 supplements for patients with non-alcoholic fatty liver disease (nafld) was proposed. the purpose of this study was to review the relationship between omega-3 fatty acids intake and nafld. methods: in this study, the terms such as nafld, omega-3 fatty acids, docosahexanoic acid, an...

Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease (CLD). Omega-3 fatty acids and antioxidants co-supplementation have been considered as an alternative treatment in NAFLD. This trial will evaluate camelina sativa oil (CSO) effects as a rich source of omega-3 fatty acids and antioxidants on cardiometabolic risk factors, metabolic endotoxemia, liver en...

Background/Aim: Non-alcoholic fatty liver disease (NAFLD) refers to the accumulation of hepatic steatosis not due to excess alcohol consumption.It is the most common liver condition in the world.The prevalence of NAFLD is up to 30% in developed countries and nearly 10% in developing nations. The aim of this study is to assess serum alpha-fetoprotein triglyceride, and total cholesterolamong Suda...

Non-alcoholic fatty liver had been believed to be a non-progressive benign disease. However, Ludwig et al. described some patients who exhibited progressive steatohepatitis without habitual alcohol drinking (Ludwig et al., 1980) and referred to this disease as non-alcoholic steatohepatitis (NASH). Later, NASH and non-progressive simple steatosis patients were included in the single disease enti...