The principle of physical causal closure makes the problem ontology consciousness insoluble since rejects possibility mental causation. However, this is based on linear causality model foundation which connection material events with each other. article deals causation non-material events, reflecting influence probability probability, and not an event event. A hypothetical considered, in one st...

BACKGROUND AND PURPOSE Rapidly progressive dementia (RPD) is an emergency in cognitive neurology, defined as cognitive impairment affecting the daily living activities developed over less than 1 year. This study investigated the profile of patients with rapidly progressive dementia at first presentation. METHODS Retrospective case analysis was done in 187 patients with rapidly progressive dem...

Acquisition of a complex immune system during evolution provided organisms with the most effective defense mechanism against "foreign" or "non-self" invaders. This efficient protection against pathogens, however, has been achieved at the expense of a higher risk for "self"-directed reaction or autoimmunity. Establishment of self-tolerance and homeostasis in the immune system is regulated at dif...

BACKGROUND Exposure to ozone activates innate immune function and causes neutrophilic (PMN) airway inflammation that in some individuals is robustly elevated. The interplay between immuno-inflammatory function and genomic signaling in those with heightened inflammatory responsiveness to ozone is not well understood. OBJECTIVES Determine baseline predictors and post exposure discriminators for...

Phenotypic variability is a hallmark of diseases involving chromosome gains and losses, such as Down syndrome and cancer. Allelic variances have been thought to be the sole cause of this heterogeneity. Here, we systematically examine the consequences of gaining and losing single or multiple chromosomes to show that the aneuploid state causes non-genetic phenotypic variability. Yeast cell popula...

With the decline in the frequency of rhesus isoimmunisation, hydrops fetalis secondary to other factors is becoming increasingly recognised. We describe a case in association with chorioangioma of the placenta. The causes of non immune hydrops are reviewed and the problems of management discussed.

Exposure of the skin to UV radiation causes local and systemic immunosuppression through vitamin D and non-vitamin D pathways. This has implication for skin cancer development, autoimmune diseases and vaccination. New studies are exploring the clinical and public health importance of UV-induced immune suppression.