Two young girls with hirsutism and premature pubarche showed nonclassical 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) deficiency. Post-ACTH increased serum delta 5-17-hydroxypregnenolone and increased ratio of delta 5-17-hydroxypregnenolone/17-hydroxyprogesterone are the most sensitive indicators of nonclassical 3 beta-HSD deficiency. Nonclassical 3 beta-HSD deficiency may not be uncommon,...

We derive simple practical procedures revealing the quantum behavior of angular momentum variables by the violation of classical upper bounds on the statistics. Data analysis is minimum and definite conclusions are obtained without evaluation of moments, or any other more sophisticated procedures. These nonclassical tests are very general and independent of other typical quantum signatures of n...

INTRODUCTION Both nonclassical and intermediate monocytes have been implicated in different inflammatory conditions. We hypothesized that these monocytes would increase during pregnancy, a condition associated with generalized activation of inflammatory responses and that they would increase even more during preeclampsia, in which inflammatory responses are further stimulated. In the present st...

ABSTRACT Several works on nonclassical fullerenes with heptagons have mainly considered the case with just one heptagon. In this context the isolated pentagon rule is not satisfied. The study of nonclassical fullerenes is important because some of them are more stable than the corresponding classical isomers with the same number of pentagonal bonds. We present several nonclassical fullerenes wi...

Robust performance of control schemes for open quantum systems is investigated under classical uncertainties in the generators dynamics and nonclassical due to decoherence initial state preparation errors. A formalism developed measure based on transmission a dynamic perturbation or error error. This makes it possible apply tools from robust such as structured singular value analysis. difficult...

We introduce a new nonclassical Riemann solver for scalar conservation laws with concave-convex flux-function. This solver is based on both a kinetic relation, which determines the propagation speed of (undercompressive) nonclassical shock waves, and a nucleation criterion, which makes a choice between a classical Riemann solution and a nonclassical one. We establish the existence of (nonclassi...

In humans, the monocyte pool comprises three subsets (classical, intermediate, and nonclassical) that circulate in dynamic equilibrium. The kinetics underlying their generation, differentiation, and disappearance are critical to understanding both steady-state homeostasis and inflammatory responses. Here, using human in vivo deuterium labeling, we demonstrate that classical monocytes emerge fir...

We consider nonclassical entropy solutions to scalar conservation laws with concaveconvex flux functions, whose set of leftand right-hand admissible states ul, ur across undercompressive shocks is selected by a kinetic function ur = φ(ul). We introduce a new definition for the (generalized) strength of classical and nonclassical shocks, allowing us to propose a generalized notion of total varia...