Purpose: To investigate the expression profile and prognostic value of SLC6A10P in patients with nonsmall cell lung cancer (NSCLC). Patients and methods: TCGA datasets were used to investigate the differential expression of SLC6A10P in NSCLC, lung adenocarcinoma (LUAD), and lung squamous cell carcinoma (LUSC). Expression of SLC6A10P was measured by in situ hybridization in tissue microarrays co...

Background/aAim: Locoregional recurrence in lung cancer still remains an important problem. We aimed to indicate the effectiveness of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for reevaluation previously treated nonsmall cell (NSCLC). Materials and methods: NSCLC patients who underwent EBUS rebiopsy suspicious recurrent or progressive lesions between January 2...

OBJECTIVE To analyze surgical and pathological parameters and outcome and prognostic factors of patients with nonsmall cell lung cancer (NSCLC) who were admitted to a single institution, as well as to correlate these findings to the current staging system. METHOD Seven hundred and thirty seven patients were diagnosed with NSCLC and admitted to Hospital do Cancer A. C. Camargo from 1990 to 200...

Combined pulmonary fibrosis and emphysema (CPFE) is defined as upper lobe emphysema and lower lobe fibrosis, which are representative lung disorders that increase the prevalence of lung cancer. This unique disorder may affect the morbidity and mortality during the early period after surgery. The present study aimed to identify which clinicopathological features significantly affect early surgic...

Lung cancer is the most common cause of cancer-related deaths worldwide, as 2.1 million people were diagnosed with disease and 1.8 passed away from lung worldwide in 2018.[1] The condition split into two sections: Small Cell Cancer (SCLC) Non-Small (NSCLC). In this research paper, I discuss key aspects NSCLC, including risk factors, symptoms, diagnosis, treatment, prevention, epidemiology. Last...

miRNAs have been proposed to be key regulators of progression and metastasis in cancer. However, an understanding of their roles and molecular mechanisms is needed to provide deeper insights for better therapeutic opportunities. In this study we investigated the role and mechanism of miR-493 in the development and progression of nonsmall-cell lung cancer (NSCLC). Our data indicated that the exp...

Background/aim: Oligometastatic disease for nonsmall cell lung cancer (NSCLC) patients is generally thought to represent a better prognosis with quieter biology, limited number of sites and long-term control. In this study, we aimed determine the efficacy radical treatment options oligometastatic NSCLC. Materials methods: This retrospective trial included totally 134 The presence oncodriver mut...

BACKGROUND Lymph node status of patients with early-stage nonsmall cell lung cancer has an influence on the choice of surgery. To assess the lymph node status more correspondingly and accurately, we evaluated the relationship between the preoperative clinical variables and lymph node status and developed one model for predicting lymph node involvement. METHODS We collected clinical and dissec...

There is a marked survival advantage for patients with nonsmall cell lung cancer (NSCLC) expressing high numbers of macrophages in their tumour islets. The primary aim of the present study was to determine the immunological phenotype of NSCLC-associated macrophages. CD68(+) macrophages expressing markers of a cytotoxic M1 phenotype or a noncytotoxic M2 phenotype were identified in the islets an...

Each year, the American Cancer Society estimates numbers of new cancer cases and deaths in United States compiles most recent data on population-based occurrence. Incidence (through 2017) were collected by Surveillance, Epidemiology, End Results Program; National Program Registries; North Association Central Registries. Mortality 2018) Center for Health Statistics. In 2021, 1,898,160 608,570 ar...