Emerging evidence has documented comorbidity between posttraumatic stress disorder (PTSD) and obsessive-compulsive disorder (OCD) among individuals with a history of traumatic events. There is growing recognition of the importance of disgust in each of these conditions independently. No study, however, has examined the potential role of disgust in these conditions following traumatic event expo...

Perineural invasion (PNI) is a pathological feature of many cancers associated with poor outcomes, metastases, and recurrence. In relation to ovarian cancer (OC), there no information about PNI’s role mechanisms. Our study found that patients PNI-positive symptoms had significantly shorter overall survival (OS) time than PNI-negative symptoms. Multivariate analyses demonstrated PNI represented ...

Obsessive compulsive disorder (OCD) is a disabling and prevalent disorder with a variety of clinical presentations and obsessional themes. Recently, research has begun to investigate relationship-related obsessive–compulsive (OC) symptoms including relationship-centered and partner-focused OC symptoms. In this paper, we present relationship obsessive–compulsive disorder (ROCD), delineate its ma...

The ferret is a suitable small animal model for preclinical evaluation of efficacy of antiviral drugs against various influenza strains, including highly pathogenic H5N1 viruses. Rigorous pharmacokinetics/pharmacodynamics (PK/PD) assessment of ferret data has not been conducted, perhaps due to insufficient information on oseltamivir PK. Here, based on PK data from several studies on both uninfe...

INTRODUCTION Obsessive-Compulsive Disorder (OCD) is a complex and heterogeneous neuropsychiatric syndrome. Contamination obsessions and washing/cleaning compulsions are the most frequent clinical OCD subtypes. The current study aimed at examining the neuropsychological impairments in drug-naive obsessive-compulsive (OC) washers without depressive symptoms and their association with the severity...

Objective: The present study examines the pattern of changes in temperament and character profiles of Obsessive Compulsive Disorder (OCD) patients following 8-20 weeks of treatment for obsessive compulsive symptoms (OC symptoms). Methodology: The study also investigated the relationship between the temperament and character pattern and the severity of OC symptoms. A sample of 52 patients who me...

cognitive models of obsessive-compulsive disorder (ocd) posit that specific kinds of dysfunctional beliefs underlie the development of this disorder. the aim of present study was to determine whether these beliefs are endorsed more strongly by ocd patients than by those with other anxiety disorders and by community samples. a battery of questionnaires, including the obq-44, moci, bdi-ii, bai, s...

Malignant peritoneal mesotheliomas (MPMs) are rare and progressive tumors, which may present similarly to primary peritoneal carcinoma or ovarian carcinoma (OC). The current study reports two cases of MPM that initially presented with the features of OC, for which paired box 8 (PAX8) immunostaining was found to be useful for diagnosis. The two patients were women, aged 58 and 56 years, respecti...

BACKGROUND Resemblance between spouses can be due to phenotypic assortment, social homogamy and/or marital interaction. A significant degree of assortment can have consequences for the genetic architecture of a population. We examined the existence and cause(s) of assortment for obsessive-compulsive (OC), anxious and depressive symptoms in a population-based twin-family sample. METHOD OC, anx...

Abstract Increased mental-health symptoms as a reaction to stressful life events, such the Covid-19 pandemic, are common. Critically, successful adaptation helps reduce baseline, preventing long-term psychiatric disorders. It is thus important understand whether and which show transient elevations, persist become chronically heightened. At particular risk for latter trajectory symptom dimension...