Fingertip response to trauma represents a fascinating example of tissue regeneration. Regeneration derives from proliferative mesenchymal cells (blastema) that subsequently differentiate into soft and skeletal tissues. Clinically, conservative treatment of the amputated fingertip under occlusive dressing can shift the response to tissue loss from a wound repair process towards regeneration. Whe...

BACKGROUND The physiopathogenesis of proliferative scarring in human skin is not well understood. Furthermore, knowledge of the precise mechanisms of action for physical treatment modalities is limited. Compression garments, occlusive/adhesive skin taping, and silicone gel sheets are applied to form an occlusion on the scar surface, reduce tension, and/or increase pressure on the scar itself. T...

The combination of light and chemicals to treat skin diseases is widely practiced in the field of dermatology, and has led to the concept of photodynamic therapy in recent years. In PDT for skin cancer, 5-aminolevulinic acid is applied topically to the affected area to be absorbed percutaneously through passive diffusion, and typically requires 4–6 h before performing PDT. In this study, we att...

BACKGROUND Recent years have seen an increase in the off-label use of photodynamic therapy for the treatment of a variety of skin diseases. Plaque-phase mycosis fungoides is among the most promising possibilities for the use of this treatment. OBJECTIVES To evaluate the treatment of plaque-phase mycosis fungoides with photodynamic therapy and compare the results obtained using fluorescence ph...

Constrained independent component analysis (CICA) is capable of eliminating the order ambiguity that is found in the standard ICA and extracting the desired independent components by incorporating prior information into the ICA contrast function. However, the current CICA method produces constraints that are based on only one type of prior information (temporal/spatial), which may increase the ...

An audit of resource use was undertaken in 35 patients treated by two ambulatory wound care providers in Germany (one medical practice and one outpatient wound clinic). A new wound dressingi was introduced with appropriate education and training in its use, and the frequency of dressing change and types of dressings used were recorded before and after adopting the new approach. Clinicians’ view...

800x600   introduction:  many items are needed for dressing including sterile dressing set, antiseptic and washing solutions, leucoplast tape, waste bin for infectious garbage, waste bin for noninfectious garbage, safe disposal trash for sharp cutting instruments, bedpan and sometimes drugs. all the items are laid out on a simple wheeled trolley. the multiplicity of items together with problems...