AIM Two prospective studies were carried out in order to investigate (1) the rise in intraocular pressure (IOP) following peribulbar anaesthesia with a fixed volume of anaesthetic agent administered by a single surgeon, and (2) the efficacy of ocular compression with the Honan balloon for lowering IOP. Glaucomatous eyes were excluded from both studies. METHODS In study group 1, 36 eyes of 36 ...

Evisceration and enucleation have been acceptable therapeutic modalities to treat not only severe ocular trauma but also various conditions, such as intraocular tumors, endophthalmitis, blind-painful-cosmetically disfiguring eyes, over the last two centuries. Clinical indications choices of procedure, whether or evisceration, vary among institutions, surgeon experience, severity structure loss....

BACKGROUND Corticosteroids play a major role in the treatment of many diseases of the posterior ocular segment. Systemically or topically administered steroids usually do not attain therapeutic concentrations in the retina, as they must first cross the blood-retina barrier. Intravitreal application is a useful alternative means of achieving therapeutic concentrations in the posterior segment bu...

S. Manna, J. J. Augsburger, Z. M. Correa, J. A. Landero, P. Kodali, R. K. Banerjee University of Cincinnati Purpose Intraocular Lymphoma (IOL) is a rare form of lymphoma which is encountered in ocular oncology practice. In recent years, the most preferred treatment has been intravitreal MTX injection, which often results in undesired systemic toxicity. A sustained release device to administer t...

PURPOSE To report the initial efficacy results of the Retina Implant Alpha AMS (Retina Implant AG, Reutlingen, Germany) for partial restoration of vision in end-stage retinitis pigmentosa (RP). DESIGN Prospective, single-arm, investigator-sponsored interventional clinical trial. Within-participant control comprising residual vision with the retinal implant switched ON versus OFF in the implan...

Diabetic macular edema (DME) is the leading cause of sight-threatening complication in diabetic patients, and several treatment modalities have been developed and evaluated to treat this pathology. Intravitreal agents, such as anti-vascular endothelial growth factors (anti-VEGF) or corticosteroids, have become more popular in recent years and are widely used for treating DME. Sustained release ...

With 30 million interventions a year worldwide, cataract surgery is one of the most frequently performed procedures. Yet, no tool currently allows teaching all steps of the procedure without putting patients at risk. A particularly challenging stage of this surgery deals with the injection and deployment of the intra-ocular lens implant. In this paper we propose to rely on shell theory to accur...