نتایج جستجو برای: ocular tumors
تعداد نتایج: 232931 فیلتر نتایج به سال:
Our findings that PlGF is a cancer target and anti-PlGF is useful for anticancer treatment have been challenged by Bais et al. Here we take advantage of carcinogen-induced and transgenic tumor models as well as ocular neovascularization to report further evidence in support of our original findings of PlGF as a promising target for anticancer therapies. We present evidence for the efficacy of a...
purpose : granular cell tumors (gct) are benign unusual neoplasms which have been proven to have a schwann cell phenotype. they rarely occur in the eye region. case reports : we report three cases of gct in the ocular adnexa including palpebra, subconjuctiva and orbit which rarely occur. patients are, a young girl with the lesion in orbit and presentation of proptosis, a middle aged man with th...
Most orbital tumors are nonmalignant. Nonmalignant orbital tumors can arise from any of the structures within the orbit, including blood vessels, fat, nerves, lacrimal gland, and connective tissue. Nonmalignant orbital tumors can be grouped into cystic lesions, vascular tumors, lymphoproliferative lesions, inflammatory lesions, mesenchymal tumors, neurogenic tumors, and lacrimal gland tumors. A...
purpose: the aim of the present study was to detect the expression of p-glycoprotein (p-gp) and multi-drug resistance associated protein 1 (mrp1) in retinoblastoma tumors, and analyze the relationship between its expression, the clinico-pathological features and recurrence. methods: p-gp and mrp1 expression in formalin-fixed paraffin-embedded retinoblastoma bearing ocular tissue sections from 2...
ocular involvement is seen in approximately 25% of patients with sarcoidosis. uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. orbital manifestations of sarcoidosis are uncommon with few series in the literature. a 65-year-old woman presented with redness of the right eye and painless, unilateral eyelid swelling. orbital scanning revealed mass in...
PURPOSE Incurable metastases develop in approximately 50% of patients with uveal melanoma (UM). The purpose of this study was to analyze genomic profiles in a large series of ocular tumors and liver metastases and design a genome-based classifier for metastatic risk assessment. METHODS A series of 86 UM tumors and 66 liver metastases were analyzed by using a BAC CGH (comparative genomic hybri...
BACKGROUND Patients with xeroderma pigmentosum (XP) are strongly predisposed to the development of numerous cutaneous cancers. However, the extent of ocular pathology in these patients has not been adequately studied. METHODS We conducted a retrospective study of tumors involving the ocular surface and ocular adnexa from 6 XP patients. Histopathological evaluation and immunohistochemistry was...
BACKGROUND AND PURPOSE Ocular masses represent a spectrum of malignant tumors and benign lesions that are sometimes difficult to detect and differentiate by conventional imaging techniques. The aim of this study was to characterize a group of malignant ocular masses with DWI, with the goals of establishing reference data and identifying potential clinical applications for improved noninvasive c...
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