BACKGROUND Digitalis-like sodium pump ligands (SPLs) effect natriuresis via inhibition of renal tubular Na(+),K(+)-ATPase but may induce vasoconstriction. The present study investigated the potential roles of 2 putative endogenous SPLs, an ouabain-like compound (OLC) and an alpha(1) Na(+),K(+)-ATPase inhibitor, marinobufagenin (MBG), in regulating natriuresis and blood pressure (BP) responses t...

Frequency control is traditionally done on the generation side. Recently we have formulated an optimal load control (OLC) problem and derived a load-side primary frequency control as a primal-dual solution to OLC. The load-side control rebalances power and resynchronize frequencies after a disturbance but cannot restore the nominal frequency. In this paper we modify OLC and derive from it a fre...

Cultural (organizational learning culture) and behavioral (organizational citizenship behaviors) antecedents of knowledge sharing are discussed in the present study. Data was collected from 402 employees of Malaysia. Structural equation model confirms that OLC was positively related to OCB and knowledge sharing. OCB was also found to perform the role of mediator between OLC and knowledge sharing.

The quantum system under periodical modulation is the simplest path to understand nonequilibrium because it can be well described by effective static Floquet Hamiltonian. Under stroboscopic measurement, initial phase usually irrelevant. However, if two uncorrelated parameters are modulated, their relative cannot gauged out so that physics dramatically changed. Here, we simultaneously modulate f...

Despite extensive research, the degree to which organizations are successful in creating strategic advantage with ERP systems, and the factors that distinguish successful and unsuccessful ERP implementations are still equivocal. Using a lens of the Resource-Based View of the firm, and following studies that suggest that IT become valuable over time when they interact with other organizational r...

BACKGROUND The open lung concept (OLC) is a method of ventilation intended to maintain end-expiratory lung volume by increased airway pressure. Since this could increase right ventricular afterload, we studied the effect of this method on right ventricular afterload in patients after cardiac surgery. METHODS We studied 24 stable patients after coronary artery surgery and/or valve surgery with...

Central nervous system (CNS) effects of mineralocorticoids participate in the development of salt-sensitive hypertension. In the brain, mineralocorticoids activate amiloride-sensitive sodium channels, and we hypothesized that this would lead to increased release of ouabainlike compounds (OLC) and thereby sympathetic hyperactivity and hypertension. In conscious Wistar rats, intracerebroventricul...

Andrews's recent proof of the Mills-Robbins-Rumsey conjectured formula for the number of totally symmetric self-complementary plane partitions is used to derive a new multi-variate constant term identity, reminiscent of, but not implied by, Macdonald's BC,-Dyson identity. The method of proof consists in translating to the language of constant terms an expression of Doran for the desired number ...

BACKGROUND Two mammalian digitalis-like factors, an ouabain-like compound (OLC) and marinobufagenin (MBG), exhibit specificity to alpha-3 and alpha-1 Na(+),K(+)-ATPase isoforms, respectively. We compared regulation of MBG and OLC by acute NaCl loading in Dahl salt-sensitive (DS) and salt-resistant (DR) rats. METHODS AND RESULTS An intraperitoneal NaCl load (0.8 g/kg) was given to adult male r...