Glial cells exist throughout the nervous system, and play essential roles in various aspects of neural development and function. Distinct types of glia may govern diverse glial functions. To determine the roles of glia requires systematic characterization of glia diversity and development. In the adult Drosophila central brain, we identify five different types of glia based on its location, mor...

The primary olfactory nervous system is unique in that it continuously renews itself and regenerates after injury. These properties are attributed to the presence of olfactory glia, termed olfactory ensheathing cells (OECs). Evidence is now emerging that individual OEC populations exist with distinct anatomical localisations and physiological properties, but their differential roles have not be...

introduction: spinal cord injuries (sci) lead to permanent irreversible functional deficits.  poor prognosis of patients is the motivation of searching a treatment for the chronic injury.  planting stem cells provides us with a promising strategy. in the meanwhile, the use of olfactory ensheathing cells (oecs) has shown very good results.  this study aims at evaluating the effect of transplante...

NEUROSCIENCE Correction for “Fibroblast growth factor signaling instructs ensheathing glia wrapping of Drosophila olfactory glomeruli,” by Bing Wu, Jiefu Li, Ya-Hui Chou, David Luginbuhl, and Liqun Luo, which was first published July 3, 2017; 10.1073/pnas.1706533114 (Proc Natl Acad Sci USA 114:7505–7512). The authors note that an additional affiliation should be listed for Bing Wu. The new affi...

The origin of GnRH-1 cells and olfactory ensheathing cells has been controversial. Genetic Cre-lox lineage tracing of the neural crest (NC) versus ectodermal contribution to the developing nasal placode was performed using two complementary mouse models, the NC-specific Wnt1Cre mouse line and an ectodermal-specific Crect mouse line. Using these lines we prove that the NC give rise to the olfact...

The Effect of Silybinin on the Expression Vascular Endothelial Growth Factor (VEGF) and Integrin-linked kinase (ILK) in Olfactory Ensheathing Cells under Normal High Glucose Conditions