نتایج جستجو برای: oligosaccharides

تعداد نتایج: 10174  

Journal: :Journal of the American Society for Mass Spectrometry 2008
Zhenqing Zhang Jin Xie Jian Liu Robert J Linhardt

Isobaric oligosaccharides enzymatically prepared from hyaluronic acid (HA) and N-acetylheparosan (NAH), were distinguished using tandem mass spectrometry. The only difference between the two series of oligosaccharides was the linkage pattern (in HA 1-->3 and in NAH 1-->4) between glucuronic acid and N-acetylglucosamine residues. Tandem mass spectrometry afforded spectra in which glycosidic clea...

Journal: :Infection and immunity 1984
H J Jennings C Lugowski F E Ashton

Oligosaccharides were obtained by the mild acid hydrolysis of the lipopolysaccharides from a number of different strains of Neisseria meningitidis, serotypes L2, L3, L4, L5, and L10. The dephosphorylated oligosaccharides were conjugated to tetanus toxoid as their 2-(4-isothiocyanatophenyl)-ethylamine derivatives, which resulted in the incorporation of from 18 to 38 oligosaccharides per molecule...

Journal: :Carbohydrate research 2013
Shuhei Yamada Keiichiro Matsushima Haruo Ura Nobuyuki Miyamoto Kazuyuki Sugahara

The biological functions of chondroitin sulfate (CS) are executed by the interaction of specific oligosaccharide sequences in the polysaccharide chain with effective proteins. Thus, CS oligosaccharides are expected to have pharmacological applications. Furthermore, the demand for CS in health food supplements and medication is growing. However, the absorbency of CS polysaccharides in the digest...

Journal: :The Journal of Cell Biology 1988
J J Neefjes J M Verkerk H J Broxterman G A van der Marel J H van Boom H L Ploegh

Recycling of a number of glycoproteins along the site of action of mannosidase I (the distal endoplasmic reticulum/cis-Golgi) was followed in several different cell lines. Treatment of cells with 1-deoxymannojirimycin (dMM) produced high mannose oligosaccharides at positions otherwise occupied by complex-type oligosaccharides in these glycoproteins. Conversion of high-mannose-type oligosacchari...

2010
Jing Ji Ling-chong Wang Hao Wu

Marine ecosystems can be considered as a rather unexplored source of drugs as well as a surprising reservoir of bioactive oligosaccharide. Marine oligosaccharides could be obtained by hydrolysis of polysaccharide existing in a variety of biomass sources or synthesized by simple oligosaccharides. In recent years, marine oligosaccharides which degraded by polysaccharides are attracting increasing...

Journal: :Histology and histopathology 2006
S Desantis G Ventriglia D Zubani M Deflorio P Megalofonou F Acone A Zarrilli G Palmieri G De Metrio

The localization and characterization of oligosaccharide sequences in the cat testis was investigated using 12 lectins in combination with the beta-elimination reaction, N-Glycosidase F and sialidase digestion. Leydig cells expressed O-linked glycans with terminal alphaGalNAc (HPA reactivity) and N-glycans with terminal/internal alphaMan (Con A affinity). The basement membrane showed terminal N...

Hamed Ghafari Farsani , Hasan Nezhadheydari, Mohammad Forouhar Vajargah, Mohammad Hasan Gerami, Seyed Aliakbar Hedayati,

Background: To assess the toxicity of environmental pollutants in fish, there are different physiological parameters including histology. This study aimed to investigate the effect of prebiotic dietary supplement on fish immune response after exposure to toxicant. Methods: The study was conducted in the Gorgan University of Agricultural and Natural Resources aquaculture Laboratory in 2017. Com...

Journal: :Glycobiology 2009
Tadasu Urashima Go Odaka Sadaki Asakuma Yusuke Uemura Kohta Goto Akitsugu Senda Tadao Saito Kenji Fukuda Michael Messer Olav T Oftedal

Neutral and acidic oligosaccharides were isolated from the milk or colostrum of four great ape species (chimpanzee (Pan troglodytes), bonobo (Pan paniscus), gorilla (Gorilla gorilla), and orangutan (Pongo pygmaeus)) and one lesser ape species (siamang (Symphalangus syndactylus)), and their chemical structures were characterized by (1)H-NMR spectroscopy. Oligosaccharides containing the type II u...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1982
R Datema P A Romero G Legler R T Schwarz

The alpha-glucosidase inhibitor bromoconduritol (6-bromo-3,4,5-trihydroxycyclohex-1-ene) inhibits trimming of the innermost glucose residue from the Glc3Man9GlcNAc2 precursor of high-mannose and complex oligosaccharides. This inhibition occurs both in intact cells and with a microsomal enzyme preparation. The formation of lipid-linked oligosaccharides was increased in glucosidase-inhibited cell...

Journal: :Carbohydrate research 2009
Toshihiko Toida Kenji Sato Noriko Sakamoto Shinobu Sakai Saori Hosoyama Robert J Linhardt

It is essential to establish a library of glycosaminoglycan oligosaccharides from the chondroitin and dermatan sulfates to investigate their biological functions and structure-activity relationships (SARs). There are several approaches to obtain oligosaccharides using chemical and enzymatic degradation procedures; however, purification of each resulting oligosaccharide is complicated because of...

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