To elucidate the specific influence of prolactin on neutral lipids in Leydig, Sertoli and germ cell compartments of the testis in immature and mature monkeys, the present study was carried out by injecting ovine prolactin (oPRL) (1 mg/kg body weight/twice daily for 10 days ip), to both age groups. Similarly, bromocryptine (an ergot alkaloid which inhibits prolactin secretion) was given to other...

At present there are strong indications that Pseudomonas aeruginosa exhibits an epidemic population structure; clinical isolates are indistinguishable from environmental isolates, and they do not exhibit a specific (disease) habitat selection. However, some important issues, such as the worldwide emergence of highly transmissible P. aeruginosa clones among cystic fibrosis (CF) patients and the ...

Leptin, the obese (Ob) gene product, is an adipocyte-derived satiety factor that is involved in the regulation of food intake and body weight. Leptin signals nutritional status to several other physiological systems and modulates their function. As PRL is involved in energy and lipid metabolism, this study was undertaken to investigate the role of PRL on in vivo regulation of leptin serum conce...

The actions of hormones on growth, cellular proliferation, and on synthetic rates of the major surfactant phospholipids, phosphatidylcholine (PC) and disaturated PC (DSPC), were studied in the lung of the chick embryo. Particular emphasis was placed on the effects of hypophysectomy, pituitary transplantation, and treatment with corticosterone (CORT). One study was concerned with hydrocortisone ...

We provide the first evidence that prolactin is a neuromodulator of behavioral and neuroendocrine stress coping in the rat. In virgin female and male rats, intracerebral infusion of ovine prolactin (oPRL) into the lateral cerebral ventricle (intracerebroventricular) exerted an anxiolytic effect on the elevated plus-maze in a dose-dependent manner (0.1 and 1.0 microg/5 microl; p < 0.01). In cont...

Hepatic glutathione S-transferase (GST) activity is increased in postpartum female rats, a phenomenon that depends on the lactation stimulus. Here we evaluated the effect of prolactin (PRL) administration on hepatic enzyme activity and on the expression of the major subunits of the a(rGSTA1, rGSTA2, rGSTA3) and m-classes (rGSTM1, rGSTM2). A similar study was conducted in lactating (LM) and in n...

I am completing a comprehensive look at the theory of orthogonal polynomials on the unit circle (OPUC; we will use OPRL for the real-line case). These two 500+-page volumes [124, 125] to appear in the same AMS Colloquium Series that includes Szegő’s celebrated 1939 book [138] contain numerous new results. Our purpose here is to discuss the most significant of these new results. Besides what we ...