The objectives of this study are 1) To review the published data and document the current knowledge on allergic manifestations to the fruit mango 2) To highlight the two distinct clinical presentations of hypersensitivity reactions caused by mango 3) To discuss the role of cross-reactivity 4) To increase awareness of potentially life threatening complications that can be caused by allergy to ma...

Specific immunotherapy (SIT) protocols for nutritional allergens have only recently been established with a focus on oral allergy syndrome because of pollen cross-reacting antibodies. For these patients, a substantial number of studies have been published suggesting benefits from SIT. The situation in true anaphylaxis to food allergens such as peanut allergy is more complex, and therapeutic str...

PURPOSE Pollen-related food allergy to fresh fruits and vegetables is a well-known clinical phenomenon. Bet v 1, the major birch pollen allergen, has been cloned and shows homologies to various food allergens (e.g. hazelnut, apple, celery, tomato). Allergy to profilin Bet v 2 was also described in 10-15% of patients sensitized to birch pollen. Objective of our work was to assess the diagnostic ...

Methods A case of oral allergy syndrome to sapodilla and custard apple was investigated following approval by Institutional Ethics Committee. Sapodilla allergy was confirmed by diagnostic tests (SPT and allergen-specific IgE). Sapodilla proteins were separated on SP-Sepharose by adsorption at pH 4 followed by step elution at pH 5 (SP1), and with increasing NaCl – 0.1 M (SP2) and 0.2 M (SP3). Fo...

Background A considerable number of pollen-allergic patients develops allergy to plant foods, which has been attributed to crossreactivity between food and pollen allergens belongs to PR-10 proteins. The majority of these patients refuse from take the foods containing PR-10 explaining bad taste or sense of itch in the mouth syndrome of oral allergy (SOA). It is assumed that the primary is sensi...

Food protein induced enterocolitis syndrome (FPIES) is a food-related non-IgE-mediated gastrointestinal hypersensitivity disorder. Atypical FPIES is characterized by the presence of specific IgE for the causative food. The guidelines suggested for diagnostic oral food challenge in pediatric patients affected by suspected FPIES are different from the ones for children with IgE-mediated food alle...

Background Pollen Food(Oral allergy) Syndrome (PFS) is a food allergy which is caused by cross-reactivity between inhalant pollen allergens and food allergens, causing mild to severe symptoms upon ingestion of the cross-reacting foods. PFS has a high and increasing prevalence in pollen-allergic patients. The role of pollen-specific immunotherapy in improving clinical outcomes for patients with ...

Cultivated strawberry (Fragaria × ananassa) is a fruity vegetable of the Rosaease family and contains allergens which cause oral allergic syndrome (OAS). OAS type I allergy mediated by IgE, as symptoms appear in cavity, hypoallergenic fruits are eagerly anticipated. The major allergen Fra 1—an ortholog birch pollen Bet v 1. It necessary to understand characteristics 1 planta properly regulate a...

OBJECTIVES To provide a review of the literature and discuss the clinical, pathophysiologic, diagnostic, and therapeutic challenges of oral allergy syndrome (OAS). DATA SOURCES English-language publications on OAS (and pollen-food allergy syndrome) were identified through MEDLINE and through the reference lists of each identified article and review. STUDY SELECTION Articles pertaining to OA...

The skin is the most frequently affected target organ in allergy or intolerance of food and food additives. The most common manifestation is acute urticaria (with or without angioedema), accounting for 40-60% of patients with IgE-mediated food allergy, whereas food additives rather aggravate chronic urticaria (intolerance provocation). The role of food allergy in the pathogenesis of atopic derm...